G
Giovanni Romeo
Researcher at University of Messina
Publications - 77
Citations - 1846
Giovanni Romeo is an academic researcher from University of Messina. The author has contributed to research in topics: Cycloaddition & Nitrone. The author has an hindex of 23, co-authored 77 publications receiving 1769 citations. Previous affiliations of Giovanni Romeo include University of Calabria & University of Catania.
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Journal ArticleDOI
Progress in the development of selective nitric oxide synthase (NOS) inhibitors.
TL;DR: The recent developments of new molecules endowed with inhibitory properties against the various isoforms of NOS are reviewed, major focus is placed on structure-activity-selectivity relationships especially concerning compounds belonging to the non-amino acid-based inhibitors.
Journal ArticleDOI
Chemical Synthesis of Heterocyclic−Sugar Nucleoside Analogues
TL;DR: Dipartimento Farmaco-Chimico, Università diMessina, Via SS Annunziata, 98168 Messina, Italy, Dipartimenti di Scienze Chimiche, Universidad de Zaragoza, CSIC, and Laboratorio de Sintesis Asimetrica are investigating how Chimiche affects Quimica Organica.
Book ChapterDOI
Microwave-assisted Chemistry of Carbohydrates
TL;DR: Microwave irradiation is becoming an increasingly popular method of heating which replaces the classical one because it proves to be a clean, cheap, and convenient method as discussed by the authors, often, it affords higher yields and results in shorter reaction times.
Journal ArticleDOI
Enantioselective Syntheses and Cytotoxicity of N,O-Nucleosides
Ugo Chiacchio,Antonino Corsaro,Daniela Iannazzo,Anna Piperno,Venerando Pistarà,Antonio Rescifina,Roberto Romeo,Vincenza Valveri,Antonio Mastino,Giovanni Romeo +9 more
TL;DR: (5'S)-5-Fluoro-1-isoxazolidin-5-yl-1H-pyrimidine-2,4-dione [(-)-AdFU], while showing low level of cytotoxicity, is a good inductor of apoptosis on lymphoid and monocytoid cells, acting as a strong potentiator of Fas-induced cell death.
Journal ArticleDOI
Synthesis of phosphonated carbocyclic 2'-oxa-3'-aza-nucleosides: novel inhibitors of reverse transcriptase.
Ugo Chiacchio,Emanuela Balestrieri,Beatrice Macchi,Daniela Iannazzo,A. Piperno,Antonio Rescifina,Roberto Romeo,Saglimbeni M,Maria Teresa Sciortino,Valveri,Antonio Mastino,Giovanni Romeo +11 more
TL;DR: Phosphonated carbocyclic 2'-oxa-3'-aza-nucleosides, while showing low levels of cytotoxicity, exert a specific inhibitor activity on two different reverse transcriptases, which is comparable with that of AZT, opening new perspectives on their possible use as therapeutic agents, in anti-retroviral and anti-HBV chemotherapy.