Giulio Maccauro

TL;DR: The microbiological diagnosis is the main predictive factor for successful treatment of pyogenic spondylodiscitis and early diagnosis and multidisciplinary management are also needed to identify underlying aggressive conditions and to avoid neurological complications associated with poorer long-term outcomes.

TL;DR: In this paper, the authors studied factors contributing to the initiation of fracture and failure of a zirconia ceramic femoral head during a revision total hip replacement, and found that failure was due to the propagation during clinical use of defects which may have been introduced into the material during the processing of the ceramic, rather than those intrinsic to zirconsia.

TL;DR: Endoprosthetic replacement of the proximal humerus provides a good function of the upper limb, a low risk of local relapse with a low complication rate at follow-up, and unreamed nailing provides immediate stability and pain relief, minimum morbidity and early return of function.

TL;DR: The results showed that failure was due to the propagation during clinical use of defects which may have been introduced into the material during the processing of the ceramic, rather than those intrinsic to zirconia.

TL;DR: In this paper, a detailed mechanism of action and the biological profiles of IL-37, the newest anti-inflammatory cytokine, are reviewed. But the authors focus on the effect of IL37 in regulating inflammatory responses, mainly by inhibiting the expression, production and function of proinflammatory cytokines: IL-1 family pro-inflammatory effects are markedly suppressed by IL37.