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Giuseppe Minniti

Researcher at University of Siena

Publications -  219
Citations -  10214

Giuseppe Minniti is an academic researcher from University of Siena. The author has contributed to research in topics: Radiation therapy & Radiosurgery. The author has an hindex of 50, co-authored 189 publications receiving 7617 citations. Previous affiliations of Giuseppe Minniti include Sapienza University of Rome & The Royal Marsden NHS Foundation Trust.

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Radiosurgery for pituitary adenomas

TL;DR: A systematic review of the literature published between 1985 and 2003 on the efficacy of radiosurgery in patients with pituitary adenomas and at least 6 months’ follow-up excluding single case reports and nonpeer-reviewed chapters is presented.
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Long-term follow-up results of postoperative radiation therapy for Cushing’s disease

TL;DR: Radiotherapy is effective in the long-term tumour- and hormone hypersecretion control of ACTH-secreting pituitary adenomas, however with a high prevalence of hypopituitarism.
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Hypofractionated radiotherapy followed by adjuvant chemotherapy with temozolomide in elderly patients with glioblastoma.

TL;DR: Hypofractionated RT followed by temozolomide may provide survival benefit maintaining a good quality of life in elderly patients with GBM and may represent a reasonable therapeutic approach especially in patients with less favourably prognostic factors.
Journal Article

Integrin Inhibitor Cilengitide for the Treatment of Glioblastoma: A Brief Overview of Current Clinical Results

TL;DR: Cilengitide, a cyclized Arg-Gly-Glu(RGD)-containing pentapeptide that selectively blocks activation of the αvβ3 and αv β5 integrins has shown encouraging activity in patients with glioblastoma as single agent, and in association with standard RT and temozolomide.