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Giuseppe Paglietti
Researcher at University of Sassari
Publications - 125
Citations - 2198
Giuseppe Paglietti is an academic researcher from University of Sassari. The author has contributed to research in topics: Quinoxaline & Ring (chemistry). The author has an hindex of 24, co-authored 125 publications receiving 2016 citations.
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Synthesis of 1-Methyl-2,3-dimethyl-N(isopropyl)carbamates-4,5-dihydro- 7-R′-8-R-1H-benzo(g)indoles and Evaluation of in vitro Anticancer Activity.
TL;DR: In this article, the synthesis of 7-mono or 7,8-disubstituted 4,5-dihydro-1-methyl-1H- benzo[g]indoles bearing a methyl-N-isopropylcarbamate group in position 2 or 2,3 of the pyrrole ring is described, in order to evaluate in vitro, anticancer activity.
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Quinoxaline Chemistry. Part 16. 4-Substituted Anilino and 4-Substituted Phenoxymethyl Pyrrolo[1,2-a]quinoxalines and N-[4-(Pyrrolo[1,2-a]quinoxalin-4-yl)amino and Hydroxymethyl]benzoyl Glutamates. Synthesis and Evaluation of in vitro Biological Activity.
Sergio Alleca,Paola Corona,Mario Loriga,Giuseppe Paglietti,Roberta Loddo,Valeria Mascia,Bernardetta Busonera,Paolo La Colla +7 more
TL;DR: In this article, pyrrolo[1,2-a]quinoxalines bearing at position 4 various substituents related to the moieties present in classical and non classical antifolic agents were prepared and evaluated in vitro for antiproliferative activity.
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Quinoxaline Chemistry. Part 8. 2-Anilino-3-carboxy-6(7)-Substituted Quinoxalines as Non Classical Antifolate Agents. Synthesis and Evaluation of in vitro Anticancer, Anti-HIV and Antifungal Activity.
TL;DR: Preliminary screening performed at NCI showed that most derivatives exhibited a moderate to strong growth inhibition activity on various tumor panel cell lines between 10(-5) and 10(-4) molar concentrations.
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4‐Substituted Anilino Imidazo[1,2‐a] and Triazolo[4,3‐a]quinoxalines. Synthesis and Evaluation of in vitro Biological Activity.
Paola Corona,Gabriella Vitale,Mario Loriga,Giuseppe Paglietti,Paolo La Colla,Gabriella Collu,Giuseppina Sanna,Roberta Loddo +7 more
TL;DR: In this paper, 15 imidazo[1,2-a] and [1, 2,4]triazolo[4,3a]quinoxalines were prepared and evaluated in vitro antimicrobial, antiviral and antiproliferative activities.
Journal Article
Synthesis of 1-methyl-2,3-dimethyl-N(isopropyl)carbamates-4,5-dihydro-7-R'- 8-R-1H-benzo[g]indoles and evaluation of in vitro anticancer activity.
TL;DR: The preliminary results of this screening at the NCI of Bethesda showed a certain cellular subpanel selectivity between 10(-5) and 10(-4) molar concentrations.