Glenda MacQueen

TL;DR: The Canadian Network for Mood and Anxiety Treatments published guidelines for the management of bipolar disorder in 2005, with updates in 2007 and 2009, and this third update, in conjunction with the International Society for Bipolar Disorders, reviews new evidence and is designed to be used in conjunctionWith the previous publications.

TL;DR: Findings are consistent with recent studies measuring CREB levels in this same subject sample, and support current animal and cellular models of antidepressant function.

TL;DR: A meta-analysis of studies that used magnetic resonance imaging to assess the volume of the hippocampus and related structures in patients with major depressive disorder found inclusion of the amygdala with the hippocampus appears to have decreased the likelihood of detecting volumetric differences in either structure.

TL;DR: These 2018 CANMAT and ISBD Bipolar Treatment Guidelines represent the significant advances in the field since the last full edition was published in 2005, including updates to diagnosis and management as well as new research into pharmacological and psychological treatments.

TL;DR: Comparing hippocampal function, as assessed by performance on hippocampal-dependent recollection memory tests, and hippocampal volumes, as measured in a 1.5-T magnetic resonance imager, in depressed subjects experiencing a postpubertal onset of depression revealed a significant logarithmic association between illness duration and hippocampusal volume.