Glenn Barnes

TL;DR: It is proposed that obesity-related insulin resistance is, at least in part, a chronic inflammatory disease initiated in adipose tissue, and that macrophage-related inflammatory activities may contribute to the pathogenesis of obesity-induced insulin resistance.

TL;DR: The results suggest a candidate region containing six genes but also highlight the complexities of LD mapping of common disorders, as well as evaluation of haplotypes in pedigree CR001.

TL;DR: In this article, the authors present methods and compositions for the diagnosis and treatment of metabolic disorders including, but not limited to, obesity, diabetes, and overweight insulin resistance, and also provide methods for identifying a compound capable of modulating a metabolic activity.

TL;DR: In this article, a method and compositions for diagnosing and treating neuropsychiatric disorders, such as schizophrenia, schizoaffective disorder, bipolar affective disorder, unipolar affective disorders and adolescent conduct disorder, are presented.

TL;DR: In this article, the discovery of polymorphisms within the 5-lipoxygenase gene which are included in a haplotype is described, and a method for identifying specific alleles of polymorphic regions of a 5-LO gene, which can be used to determine whether a patient has a more or less severe phenotype of an inflammatory disease or disorder such as asthma.