G
Gloria E. Meredith
Researcher at Rosalind Franklin University of Medicine and Science
Publications - 82
Citations - 6704
Gloria E. Meredith is an academic researcher from Rosalind Franklin University of Medicine and Science. The author has contributed to research in topics: Nucleus accumbens & Striatum. The author has an hindex of 42, co-authored 82 publications receiving 6326 citations. Previous affiliations of Gloria E. Meredith include Royal College of Surgeons in Ireland & University of Amsterdam.
Papers
More filters
Journal ArticleDOI
‘Rejuvenation’ protects neurons in mouse models of Parkinson’s disease
C. Savio Chan,Jaime N. Guzman,Ema Ilijic,Jeff N. Mercer,Caroline Rick,Caroline Rick,Tatiana Tkatch,Gloria E. Meredith,D. James Surmeier +8 more
TL;DR: In this paper, it was shown that blocking Ca(v)1.3 channels in adult neurons induces a reversion to the juvenile form of pacemaking, leading to a new strategy that could slow or stop the progression of Parkinson's disease.
Journal ArticleDOI
MPTP mouse models of Parkinson's disease: an update.
TL;DR: The ability of MPTP mouse models to replicate the pathophysiology of PD, the mechanisms ofMPTP-induced neurotoxicity, strain differences in susceptibility to MPTP, and the models' roles in testing therapeutic approaches are discussed.
Journal ArticleDOI
Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment.
TL;DR: The sustained alterations in the nigrostriatal pathway resemble the cardinal signs of human Parkinson's disease and suggest that this chronic mouse model is potentially useful to study the pathophysiology and mechanisms of Parkinsonism and should also prove useful for the development of neuroprotection strategies.
Journal ArticleDOI
Behavioral models of Parkinson's disease in rodents: A new look at an old problem
Gloria E. Meredith,Un Jung Kang +1 more
TL;DR: How investigations in rodents of skilled forepaw actions, including placing, grooming, or foot faults, have clear correlates in Parkinson's disease, and are, therefore, the most sensitive ways of detecting motor impairment following dopamine loss from the basal ganglia of rodents are explained.
Journal ArticleDOI
Morphological differences between projection neurons of the core and shell in the nucleus accumbens of the rat.
TL;DR: The differential distribution and action of various neurochemicals such as dopamine in the shell and core, supports the idea that different morphologies reflect the presence of distinct neuronal circuits in these two territories.