G
Glyn L. Devlin
Researcher at Monash University
Publications - 2
Citations - 105
Glyn L. Devlin is an academic researcher from Monash University. The author has contributed to research in topics: Protein folding & Serpin. The author has an hindex of 2, co-authored 2 publications receiving 104 citations.
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Acid Denaturation of α1-Antitrypsin: Characterization of a Novel Mechanism of Serpin Polymerization
TL;DR: The kinetics and conformational changes of alpha(1)-antitrypsin polymerization at pH 4 are characterized using tryptophan fluorescence, circular dichroism, turbidity changes and thioflavin T binding to describe a novel kinetic mechanism of serine proteinase inhibitor polymerization.
Journal ArticleDOI
A protein family under 'stress' - serpin stability, folding and misfolding.
TL;DR: The means by which the serpin can attain and preserve the most stable conformation are discussed, including the triggers for misfolding to these more stable states and the mechanisms by which it occurs.