G
Gonzalo P. Solis
Researcher at University of Geneva
Publications - 36
Citations - 1491
Gonzalo P. Solis is an academic researcher from University of Geneva. The author has contributed to research in topics: Wnt signaling pathway & Mutant. The author has an hindex of 19, co-authored 31 publications receiving 1300 citations. Previous affiliations of Gonzalo P. Solis include University of Konstanz & University of Lausanne.
Papers
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Journal ArticleDOI
Regulation of Embryonic Cell Adhesion by the Prion Protein
Edward Málaga-Trillo,Gonzalo P. Solis,Yvonne Schrock,Corinna Geiss,Lydia V. Luncz,Venus Thomanetz,Claudia A. O. Stuermer +6 more
TL;DR: Cell-transplantation experiments indicate that the regulation of embryonic cell adhesion by PrP is cell-autonomous, and evolutionarily conserved roles of PrP in cell communication are uncovered, which ultimately impinge on the stability of adherens cell junctions during embryonic development.
Journal ArticleDOI
Reggie/flotillin proteins are organized into stable tetramers in membrane microdomains.
Gonzalo P. Solis,Maja Hoegg,Christina Munderloh,Yvonne Schrock,Edward Málaga-Trillo,Eric Rivera-Milla,Claudia A. O. Stuermer +6 more
TL;DR: Reggie-1 and -2 proteins form their own type of non-caveolar membrane microdomains, which are involved in important cellular processes such as T-cell activation, phagocytosis and signalling mediated by the cellular prion protein and insulin; this is consistent with the notion that reggie micro domains promote protein assemblies and signalling.
Journal ArticleDOI
Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila.
Vladimir L. Katanaev,Gonzalo P. Solis,George Hausmann,Silke Buestorf,Natalya Katanayeva,Yvonne Schrock,Claudia A. O. Stuermer,Konrad Basler +7 more
TL;DR: In this paper, a major protein component of membrane microdomains, reggie-1/flotillin-2, plays important roles in secretion and spreading of Wnt and Hedgehog in Drosophila.
Journal ArticleDOI
Linking membrane microdomains to the cytoskeleton: regulation of the lateral mobility of reggie-1/flotillin-2 by interaction with actin.
Matthias F. Langhorst,Gonzalo P. Solis,Sylvia Hannbeck,Helmut Plattner,Claudia A. O. Stuermer +4 more
TL;DR: It is shown here that reggie‐1/flotillin‐2 microdomains are organized along cortical F‐actin in several cell types and can efficiently be immobilized by actin polymerisation, while exchange of reggie-1/ Flotillin-2 molecules between micro domains is enhanced by actIn disruption as shown by tracking of individual microdomain using TIRF microscopy.
Journal ArticleDOI
Reggies/Flotillins Regulate Retinal Axon Regeneration in the Zebrafish Optic Nerve and Differentiation of Hippocampal and N2a Neurons
Christina Munderloh,Gonzalo P. Solis,Vsevolod Bodrikov,Friederike A. Jaeger,Marianne Wiechers,Edward Málaga-Trillo,Claudia A. O. Stuermer +6 more
TL;DR: It is shown that reggies regulate axon regeneration in zebrafish after optic nerve section (ONS) in vivo as well as axon/neurite extension in hippocampal and N2a neurons in vitro through signal transduction molecules modulating actin dynamics.