University of Konstanz

About: University of Konstanz is a(n) education organization based out in Konstanz, Baden-Württemberg, Germany. It is known for research contribution in the topic(s): Population & Visualization. The organization has 12115 authors who have published 27401 publication(s) receiving 951162 citation(s). The organization is also known as: University of Constance & Universität Konstanz.

Estimating the reproducibility of psychological science

Abstract: Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available. Replication effects were half the magnitude of original effects, representing a substantial decline. Ninety-seven percent of original studies had statistically significant results. Thirty-six percent of replications had statistically significant results; 47% of original effect sizes were in the 95% confidence interval of the replication effect size; 39% of effects were subjectively rated to have replicated the original result; and if no bias in original results is assumed, combining original and replication results left 68% with statistically significant effects. Correlational tests suggest that replication success was better predicted by the strength of original evidence than by characteristics of the original and replication teams.

A faster algorithm for betweenness centrality

Abstract: Motivated by the fast‐growing need to compute centrality indices on large, yet very sparse, networks, new algorithms for betweenness are introduced in this paper. They require O(n + m) space and run in O(nm) and O(nm + n2 log n) time on unweighted and weighted networks, respectively, where m is the number of links. Experimental evidence is provided that this substantially increases the range of networks for which centrality analysis is feasible. The betweenness centrality index is essential in the analysis of social networks, but costly to compute. Currently, the fastest known algorithms require ?(n 3) time and ?(n 2) space, where n is the number of actors in the network.

A Theory of Reciprocity

Abstract: This paper presents a formal theory of reciprocity. Reciprocity means that people reward kind actions and punish unkind ones. The theory takes into account that people evaluate the kindness of an action not only by its consequences but also by the intention underlying this action. The theory explains the relevant stylized facts of a wide range of experimental games. Among them are the ultimatum game, the gift-exchange game, a reduced best-shot game, the dictator game, the prisoner's dilemma, and public goods games. Furthermore, the theory explains why the same consequences trigger different reciprocal responses in different environments Finally the theory explains why in bilaterial interactions outcomes tend to be "fair" whereas in competitive markets even extremely unfair distributions may arise.

Guidelines for using human event-related potentials to study cognition: Recording standards and publication criteria

Abstract: Event-related potentials ~ERPs! recorded from the human scalp can provide important information about how the human brain normally processes information and about how this processing may go awry in neurological or psychiatric disorders. Scientists using or studying ERPs must strive to overcome the many technical problems that can occur in the recording and analysis of these potentials. The methods and the results of these ERP studies must be published in a way that allows other scientists to understand exactly what was done so that they can, if necessary, replicate the experiments. The data must then be analyzed and presented in a way that allows different studies to be compared readily. This paper presents guidelines for recording ERPs and criteria for publishing the results.

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

Abstract: During ischemic brain injury, glutamate accumulation leads to overstimulation of postsynaptic glutamate receptors with intracellular Ca2+ overload and neuronal cell death. Here we show that glutamate can induce either early necrosis or delayed apoptosis in cultures of cerebellar granule cells. During and shortly after exposure to glutamate, a subpopulation of neurons died by necrosis. In these cells, mitochondrial membrane potential collapsed, nuclei swelled, and intracellular debris were scattered in the incubation medium. Neurons surviving the early necrotic phase recovered mitochondrial potential and energy levels. Later, they underwent apoptosis, as shown by the formation of apoptotic nuclei and by chromatin degradation into high and low molecular weight fragments. These results suggest that mitochondrial function is a critical factor that determines the mode of neuronal death in excitotoxicity.