Graham Errington

TL;DR: Estimates of exposure obtained by filter analysis and biomarkers of exposure correlate significantly over a wide range of smoke exposures and that filter analysis may provide a simple and effective alternative to biomarkers for estimating smokers' exposure are shown.

TL;DR: The developed LC-MS/MS method is suitable for the quantification of phenolic PAH metabolites of naphthalene, fluorene, phenanthrene, and pyrene in smoker and non-smoker urine and showed good specificity, sensitivity, and accuracy for the intended purpose.

TL;DR: It is demonstrated that when smokers switched from smoking combustible cigarettes to using tobacco heating products their exposure to smoke toxicants was significantly decreased, in many cases to the same extent as that seen when they quit smoking completely.

TL;DR: An LC-MS/MS method is suitable for assessing the tobacco use-related exposure to NNK, NNN, NAB and NAT and Smokers were found to have significantly higher levels of TSNA in their urine than nonsmokers.

TL;DR: This smoke exposure system is a reliable and repeatable method of generating and exposing ALI in vitro cultures to cigarette smoke and may be used as an alternative in vitro tool for evaluating other aerosols and gaseous mixtures such as air pollutants, inhaled pharmaceuticals and cosmetics.