G
Graham P. Lidgard
Researcher at Mayo Clinic
Publications - 88
Citations - 2859
Graham P. Lidgard is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Colorectal cancer & Cancer. The author has an hindex of 17, co-authored 85 publications receiving 2287 citations. Previous affiliations of Graham P. Lidgard include University of Rochester.
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Journal ArticleDOI
Multitarget Stool DNA Testing for Colorectal-Cancer Screening
Thomas F. Imperiale,David F. Ransohoff,Steven H. Itzkowitz,Theodore R. Levin,Philip T. Lavin,Graham P. Lidgard,David A. Ahlquist,Barry M. Berger +7 more
TL;DR: In asymptomatic persons at average risk for colorectal cancer, multitarget stool DNA testing detected significantly more cancers than did FIT but had more false positive results.
Journal ArticleDOI
Next-Generation Stool DNA Test Accurately Detects Colorectal Cancer and Large Adenomas
David A. Ahlquist,Hongzhi Zou,Michael J. Domanico,Douglas W. Mahoney,Tracy C. Yab,William R. Taylor,Malinda L. Butz,Stephen N. Thibodeau,Linda Rabeneck,Lawrence Paszat,Kenneth W. Kinzler,Bert Vogelstein,Niels Chr. Bjerregaard,Søren Laurberg,Henrik Toft Sørensen,Barry M. Berger,Graham P. Lidgard +16 more
TL;DR: Early-stage CRC and large adenomas can be detected throughout the colorectum and with high levels of accuracy by the sDNA test and effects of covariates on test performance are assessed.
Journal ArticleDOI
The stool DNA test is more accurate than the plasma septin 9 test in detecting colorectal neoplasia.
David A. Ahlquist,William R. Taylor,Douglas W. Mahoney,Hongzhi Zou,Michael J. Domanico,Stephen N. Thibodeau,Lisa A. Boardman,Barry M. Berger,Graham P. Lidgard +8 more
TL;DR: Based on analyses of paired samples, the sDNA test detects nonmetastatic CRC and large adenomas with significantly greater levels of sensitivity than the SEPT9 test and might be used to modify approaches for CRC prevention and early detection.
Journal ArticleDOI
Clinical performance of an automated stool DNA assay for detection of colorectal neoplasia.
Graham P. Lidgard,Michael J. Domanico,Janelle J. Bruinsma,James Light,Zubin D. Gagrat,Rebecca Oldham-Haltom,Keith D. Fourrier,Hatim T. Allawi,Tracy C. Yab,William R. Taylor,Julie A. Simonson,Mary E. Devens,Russell I. Heigh,David A. Ahlquist,Barry M. Berger +14 more
TL;DR: An automated, multi-target sDNA assay is developed that detects CRC and premalignant lesions with levels of accuracy previously demonstrated with a manual process and could be a widely accessible noninvasive approach to general CRC screening.
Journal ArticleDOI
Hepatocellular Carcinoma Detection by Plasma Methylated DNA: Discovery, Phase I Pilot, and Phase II Clinical Validation
John B. Kisiel,Brian A. Dukek,Reddappa V.S.R. Kanipakam,Hassan Ghoz,Tracy C. Yab,Calise K. Berger,William R. Taylor,Patrick H. Foote,Nasra H. Giama,Kristeen Onyirioha,Mohamed A. Abdallah,Kelli N. Burger,Seth W. Slettedahl,Douglas W. Mahoney,Thomas C. Smyrk,Jason T. Lewis,Maria Giakoumopoulos,Hatim T. Allawi,Graham P. Lidgard,Lewis R. Roberts,David A. Ahlquist +20 more
TL;DR: MDMs identified in this study proved to accurately detect HCC by plasma testing using target enrichment long‐probe quantitative amplified signal (TELQAS) assays.