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Steven H. Itzkowitz
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 270
Citations - 20501
Steven H. Itzkowitz is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Colorectal cancer & Cancer. The author has an hindex of 67, co-authored 252 publications receiving 18733 citations. Previous affiliations of Steven H. Itzkowitz include Veterans Health Administration & Columbia University.
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Journal ArticleDOI
Multitarget Stool DNA Testing for Colorectal-Cancer Screening
Thomas F. Imperiale,David F. Ransohoff,Steven H. Itzkowitz,Theodore R. Levin,Philip T. Lavin,Graham P. Lidgard,David A. Ahlquist,Barry M. Berger +7 more
TL;DR: In asymptomatic persons at average risk for colorectal cancer, multitarget stool DNA testing detected significantly more cancers than did FIT but had more false positive results.
Journal ArticleDOI
Inflammation and Cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation
Steven H. Itzkowitz,Xianyang Yio +1 more
TL;DR: Observations of mice genetically prone to inflammatory bowel disease also develop colorectal cancer especially in the presence of bacterial colonization offer compelling support for the role of inflammation in colon carcinogenesis.
Journal ArticleDOI
Intestinal inflammation and cancer
TL;DR: The genetic features that lead to sporadic CRC-chromosome instability, microsatellite instability, and DNA hypermethylation-also occur in colitis-associated CRC, offering compelling support for the role of inflammation in colon carcinogenesis.
Journal ArticleDOI
Fecal DNA versus fecal occult blood for colorectal-cancer screening in an average-risk population.
Thomas F. Imperiale,David F. Ransohoff,Steven H. Itzkowitz,Barry A. Turnbull,Michael E. Ross +4 more
TL;DR: Although the majority of neoplastic lesions identified by colonoscopy were not detected by either noninvasive test, the multitarget analysis of fecal DNA detected a greater proportion of important colorectal neoplasia than did Hemoccult II without compromising specificity.
Journal ArticleDOI
Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study.
Roopali Bansal Gupta,Noam Harpaz,Steven H. Itzkowitz,Sabera Hossain,Sierra Matula,Asher Kornbluth,Carol A. Bodian,Thomas A. Ullman +7 more
TL;DR: The severity of microscopic inflammation over time is an independent risk factor for developing advanced colorectal neoplasia among patients with long-standing UC.