G
Graham W. Taylor
Researcher at Imperial College London
Publications - 123
Citations - 6603
Graham W. Taylor is an academic researcher from Imperial College London. The author has contributed to research in topics: Leukotriene E4 & Pseudomonas aeruginosa. The author has an hindex of 41, co-authored 123 publications receiving 6418 citations. Previous affiliations of Graham W. Taylor include Royal College of Surgeons of England & Hammersmith Hospital.
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Journal ArticleDOI
Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis
Mark B. Pepys,Jeff Herbert,Winston L. Hutchinson,Glenys A. Tennent,Helen J. Lachmann,J. R. Gallimore,Laurence Lovat,Tamas Bartfai,Tamas Bartfai,Alexander Alanine,Cornelia Hertel,Torsten Hoffmann,Roland Jakob-Roetne,Roger David Norcross,J. A. Kemp,Ken Ichi Yamamura,Misao Suzuki,Graham W. Taylor,Sarah S. Murray,D Thompson,Alan Purvis,Simon Kolstoe,Steve P. Wood,Philip N. Hawkins +23 more
TL;DR: In this paper, a drug called R-1-[6]-R-2-carboxy-pyrrolidin-1-yl]-6-oxohexanoyl]-pyrroleidin]-2-Carboxylic acid (R-1]-6-[R]-R]-Pyrrolidine-2]-carboxyl acid was developed to remove SAP from human amyloid P component.
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Structure of slow-reacting substance of anaphylaxis from guinea-pig lung
TL;DR: The first spectroscopic and analytical protein chemical data on intact SRS-A are reported which allow us to define unequivocally the complete covalent structure of this immunologically generated material as the novel peptidolipid 5-hydroxy-6-cysteinyl glycinyl-7, 9, 11, 14-eicosatetraenoic acid.
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Measurement of Pseudomonas aeruginosa phenazine pigments in sputum and assessment of their contribution to sputum sol toxicity for respiratory epithelium.
TL;DR: The phenazine pigments pyocyanin and 1-hydroxyphenazine were resolved by high-pressure liquid chromatography from the sputum sol phase from 9 of 13 patients with cystic fibrosis or bronchiectasis colonized by Pseudomonas aeruginosa.
Journal ArticleDOI
Urinary leukotriene E4 after antigen challenge and in acute asthma and allergic rhinitis.
Graham W. Taylor,Peter Black,Nicholas C. Turner,Ian Taylor,NicolaH Maltby,R. W. Fuller,C.T. Dollery +6 more
TL;DR: Evidence is provided that leukotrienes are released in vivo in man after antigen challenge and in acute asthma.
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Pseudomonas aeruginosa pyocyanin and 1-hydroxyphenazine inhibit fungal growth.
TL;DR: There may be a role for pyocyanin and 1-hydroxyphenazine in the prevention of pulmonary candidiasis in patients colonised by P aeruginosa.