G
Gregory J. del Zoppo
Researcher at University of Washington
Publications - 81
Citations - 11962
Gregory J. del Zoppo is an academic researcher from University of Washington. The author has contributed to research in topics: Stroke & Ischemia. The author has an hindex of 34, co-authored 81 publications receiving 10486 citations. Previous affiliations of Gregory J. del Zoppo include Scripps Health & Scripps Research Institute.
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Journal ArticleDOI
Guidelines for the Early Management of Adults With Ischemic Stroke: A Guideline From the American Heart Association/ American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists
Harold P. Adams,Gregory J. del Zoppo,Mark J. Alberts,Deepak L. Bhatt,Lawrence M. Brass,Anthony J. Furlan,Robert L. Grubb,Randall T. Higashida,Edward C. Jauch,Chelsea S. Kidwell,Patrick D. Lyden,Lewis B. Morgenstern,Adnan I. Qureshi,Robert H. Rosenwasser,Phillip A. Scott,Eelco F.M. Wijdicks +15 more
TL;DR: In this paper, the authors provide an overview of the current evidence about components of the evaluation and treatment of adults with acute ischemic stroke and provide information for healthcare policy makers.
Journal ArticleDOI
Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials
Jonathan Emberson,Kennedy R. Lees,Patrick D. Lyden,Lisa Blackwell,Gregory W. Albers,Erich Bluhmki,Thomas G. Brott,Geoff Cohen,Stephen M. Davis,Geoffrey A. Donnan,James C. Grotta,George Howard,Markku Kaste,Masatoshi Koga,Ruediger von Kummer,Maarten G Lansberg,Richard I. Lindley,Gordon D Murray,Jean-Marc Olivot,Mark W Parsons,Barbara C. Tilley,Danilo Toni,Kazunori Toyoda,Nils Wahlgren,Joanna M. Wardlaw,William Whiteley,Gregory J. del Zoppo,Colin Baigent,Peter Sandercock,Werner Hacke +29 more
TL;DR: In this paper, a pre-specifi ed meta-analysis of individual patient data from 6756 patients in nine randomised trials comparing alteplase with placebo or open control was conducted.
Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials | NOVA. The University of Newcastle's Digital Repository
Jonathan Emberson,K.R. Lees,J Grotta,George Howard,Markku Kaste,Masatoshi Koga,Ruediger von Kummer,Maarten G. Lansberg,R.I. Lindley,G. D. Murray,Jean Marc Olivot,Mark Parsons,Patrick D. Lyden,Barbara C. Tilley,Danilo Toni,Kazunori Toyoda,Nils Wahlgren,Joanna Wardlaw,William Whiteley,Gregory J. del Zoppo,Colin Baigent,Peter Sandercock,Werner Hacke,Lisa Blackwell,Gregory W. Albers,Erich Bluhmki,Thomas Brott,Geoff Cohen,Stephen M. Davis,Geoffrey A. Donnan +29 more
TL;DR: Alteplase increased the odds of a good stroke outcome, with earlier treatment associated with bigger proportional benefit, and Proportional treatment benefits were similar irrespective of age or stroke severity.
Journal ArticleDOI
Thrombolysis for acute ischaemic stroke
TL;DR: Thrombolytic therapy, mostly administered up to six hours after ischaemic stroke, significantly reduced the proportion of participants who were dead or dependent at three to six months after stroke and increased the risk of symptomatic intracranial haemorrhage.
Journal ArticleDOI
Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis
Joanna M. Wardlaw,Veronica Murray,Eivind Berge,Gregory J. del Zoppo,Peter Sandercock,Richard L Lindley,Geoff Cohen +6 more
TL;DR: The evidence indicates that intravenous rt-PA increased the proportion of patients who were alive with favourable outcome and alive and independent at final follow-up, which strengthens previous evidence to treat patients as early as possible after acute ischaemic stroke, although some patients might benefit up to 6 h after stroke.