G
Guendalina Zuccari
Researcher at University of Genoa
Publications - 70
Citations - 1107
Guendalina Zuccari is an academic researcher from University of Genoa. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 17, co-authored 51 publications receiving 724 citations. Previous affiliations of Guendalina Zuccari include University of Bologna.
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Considerable Improvement of Ursolic Acid Water Solubility by Its Encapsulation in Dendrimer Nanoparticles: Design, Synthesis and Physicochemical Characterization
TL;DR: In this paper, the physical entrapment of Ursolic acid in a biodegradable not cytotoxic cationic dendrimer (G4K) was reported, which showed a drug loading (DL%) much higher than those previously reported, a protracted release profile governed by diffusion mechanisms, and no cytotoxicity.
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Two Novel PET Radiopharmaceuticals for Endothelial Vascular Cell Adhesion Molecule-1 (VCAM-1) Targeting.
Sara Pastorino,Sara Baldassari,Giorgia Ailuno,Guendalina Zuccari,Giuliana Drava,Andrea Petretto,Vanessa Cossu,Cecilia Marini,Silvana Alfei,Tullio Florio,Gianmario Sambuceti,Gabriele Caviglioli +11 more
TL;DR: In this paper, two novel Positron Emission Tomography (PET) radiopharmaceuticals (MacroP and NAMP), based on the VCAM-1-binding peptide having sequence VHPKQHRGGSKGC, were synthesized and characterized.
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Recommendations to Synthetize Old and New β-Lactamases Inhibitors: A Review to Encourage Further Production
Silvana Alfei,Guendalina Zuccari +1 more
TL;DR: BLEsIs are examined by a chemistry approach, reviewing both the long-established synthesis adopted to prepare the old BLEs is, those proposed to achieve the BLE’sIs that are newly approved, and those recently reported to Prepare the most relevant molecules yet in development, which have shown high potency.
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In vitro and In vivo Antitumor Activity of the Novel Derivatized Polyvinyl Alcohol-Based Polymer P10(4)
TL;DR: The data suggest that P10(4) holds promise as an anticancer compound and, because of its lack of interaction with DNA, is unlikely to give rise to drug resistance.
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Bactericidal Activity of Non-Cytotoxic Cationic Nanoparticles against Clinically and Environmentally Relevant Pseudomonas spp. Isolates.
Anna Maria Schito,Gabriella Piatti,Debora Caviglia,Guendalina Zuccari,Alessia Zorzoli,Danilo Marimpietri,Silvana Alfei +6 more
TL;DR: In this paper, a cationic water-soluble lysine dendrimer (G5-PDK) was tested on several species of Pseudomonas genus.