G
Guido Sani
Researcher at University of Florence
Publications - 96
Citations - 2479
Guido Sani is an academic researcher from University of Florence. The author has contributed to research in topics: Transplantation & Ventricular assist device. The author has an hindex of 25, co-authored 95 publications receiving 2309 citations. Previous affiliations of Guido Sani include University of Cagliari & University of Siena.
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Journal ArticleDOI
Does ministernotomy improve postoperative outcome in aortic valve operation? A prospective randomized study
TL;DR: The results showed that ministernotomy had not only important cosmetic advantages but also beneficial effects in blood loss and transfusion, postoperative pain, and probably in sternal stability.
Journal ArticleDOI
Characterization of the Hyperpolarization-Activated Current, If, in Ventricular Myocytes From Human Failing Heart
Elisabetta Cerbai,Roberto Pino,F. Porciatti,Guido Sani,Michele Toscano,Massimo Maccherini,Gabriele Giunti,Alessandro Mugelli +7 more
TL;DR: Its electrophysiological characteristics resemble those previously described in hypertrophied rat LVMs and suggest that I(f) could be an arrhythmogenic mechanism in patients with severe heart failure.
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The properties of the pacemaker current I(F)in human ventricular myocytes are modulated by cardiac disease.
Elisabetta Cerbai,Laura Sartiani,Petra DePaoli,Roberto Pino,Massimo Maccherini,Federico Bizzarri,Francesco Diciolla,Giuseppe Davoli,Guido Sani,Alessandro Mugelli +9 more
TL;DR: I(f) is overexpressed in human ventricular myocytes from failing hearts; its functional expression seems related to the etiology of the disease, being higher in ischemic than in dilated cardiomyopathy, and not to the degree of cell hypertrophy.
Journal ArticleDOI
Cardiac growth factors in human hypertrophy relations with myocardial contractility and wall stress
Gian Gastone Neri Serneri,Pietro Amedeo Modesti,Maria Boddi,Ilaria Cecioni,Rita Paniccia,Mirella Coppo,Giorgio Galanti,Ignazio Simonetti,Simone Vanni,Letizia Papa,Brunella Bandinelli,Angela Migliorini,Alessandra Modesti,Massimo Maccherini,Guido Sani,Michele Toscano +15 more
TL;DR: The present results indicate that the course of human left ventricular hypertrophy is characterized by the participation of different cardiac growth factors that are selectively related both to the type of hemodynamic overload and to ventricular function.
Journal ArticleDOI
Selective Upregulation of Cardiac Endothelin System in Patients With Ischemic but Not Idiopathic Dilated Cardiomyopathy: Endothelin-1 System in the Human Failing Heart
Gian Gastone Neri Serneri,Ilaria Cecioni,Simone Vanni,Rita Paniccia,Brunella Bandinelli,Annamaria Vetere,Xiao Janming,Iacopo Bertolozzi,Maria Boddi,Gian Franco Lisi,Guido Sani,Pietro Amedeo Modesti +11 more
TL;DR: The present results show that human ventricular myocytes express all of the components of the ET-1 system, which is selectively upregulated in ICM patients and appears to be functionally important in the maintenance of cardiac function.