Rita Paniccia

TL;DR: Nonresponsiveness to clopidogrel is a strong independent predictor of stent thrombosis in patients receiving sirolimus- or paclitaxel-eluting stents.

TL;DR: RPR, defined in the presence of P2Y12 reaction unit values above this cutoff, was found to be a significant and independent predictor of cardiovascular death and nonfatal MI in a model that adjusted for cardiovascular risk factors, renal failure, reduced left ventricular ejection fraction, multivessel disease, total stent length, bifurcation lesions, number of lesions treated, and type of stent.

TL;DR: Well-tried and innovative platelet function tests and their methodological features and clinical applications are considered and different platelet methodologies for the evaluation of inherited and acquired bleeding disorders and for monitoring antiplatelet therapies are spreading.

TL;DR: This study demonstrates, for the first time, that the *2 CYP2C19 allele is associated with higher platelet aggregability and RPR in high-risk vascular patients on dual antiplatelet treatment.

TL;DR: In this paper, the role of the CYP2C19*2 polymorphism in the occurrence of stent thrombosis or the composite end point of ST and cardiac mortality within a 6-month follow-up in patients undergoing percutaneous coronary interventions with drug-eluting stent implantation on dual-antiplatelet treatment enrolled in the RECLOSE trial.