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Guixue Zhang

Researcher at Northeast Agricultural University

Publications -  14
Citations -  151

Guixue Zhang is an academic researcher from Northeast Agricultural University. The author has contributed to research in topics: Sertoli cell & Wnt signaling pathway. The author has an hindex of 7, co-authored 13 publications receiving 84 citations.

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Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway.

TL;DR: MC-LR induced inflammatory response in bovine Sertoli cell via activation of TLR4/NF-kB signaling pathway, and upregulation of anti-inflammatory cytokines and expression of blood-testis barrier constituent proteins was observed.
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Selenium (Na2SeO3) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.

TL;DR: It is shown that selenium supplementation in the culture medium up to 0.50 mg/L concentration upregulates immune genes and blood–testis barrier constituent proteins of bovine Sertoli cells.
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Lysosomes are involved in induction of steroidogenic acute regulatory protein (StAR) gene expression and progesterone synthesis through low-density lipoprotein in cultured bovine granulosa cells

TL;DR: The results indicate that LDL promotes StAR expression, synthesis of progesterone, and formation of lysosomes in bovine granulosa cells, and lysOSomes participate in the process by releasing free cholesterol from hydrolyzed LDL.
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Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway.

TL;DR: It is indicated that WT1 mediates the regulation of several proteins involved in bovine SCs polarity maintenance and intercellular tight junctions (TJ) by non-canonical WNT signaling pathway.
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The ameliorative effect of melatonin on LPS-induced Sertoli cells inflammatory and tight junctions damage via suppression of the TLR4/MyD88/NF-κB signaling pathway in newborn calf

TL;DR: In this article, the effect of Melatonin (MT) on the protection of the blood-testicular barrier (BTB) was investigated in newborn calf Sertoli cells.