G
Gunter Schuch
Researcher at University of Hamburg
Publications - 49
Citations - 3306
Gunter Schuch is an academic researcher from University of Hamburg. The author has contributed to research in topics: Angiogenesis & Cancer. The author has an hindex of 23, co-authored 45 publications receiving 3150 citations. Previous affiliations of Gunter Schuch include Wake Forest Institute for Regenerative Medicine & Harvard University.
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In vitro differentiation of endothelial cells from AC133-positive progenitor cells
Ursula M. Gehling,Süleyman Ergün,Udo Schumacher,Christoph Wagener,Klaus Pantel,Marcus Otte,Gunter Schuch,Philippe Schafhausen,Thorsten Mende,Nerbil Kilic,Katrin Kluge,Birgit Schäfer,Dieter K. Hossfeld,Walter Fiedler +13 more
TL;DR: It is reported that human AC133+ cells from granulocyte colony-stimulating factor–mobilized peripheral blood have the capacity to differentiate into endothelial cells (ECs) and in mice with severe combined immunodeficiency, AC133-derived cells form new blood vessels in vivo when injected subcutaneously together with A549 lung cancer cells.
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Phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil, leucovorin plus either oxaliplatin or cisplatin: a study of the Arbeitsgemeinschaft Internistische Onkologie
Salah-Eddin Al-Batran,Joerg T. Hartmann,Stephan Probst,Harald Schmalenberg,S. Hollerbach,Ralf Hofheinz,Volker Rethwisch,G. Seipelt,Nils Homann,Gerhard Wilhelm,Gunter Schuch,Jan Stoehlmacher,Hans Günter Derigs,Susanna Hegewisch-Becker,Johannes Grossmann,Claudia Pauligk,Akin Atmaca,Carsten Bokemeyer,Alexander Knuth,Elke Jäger +19 more
TL;DR: In older adult patients, FLO also seemed to be associated with improved efficacy in patients with advanced gastric cancer, and in patients older than 65 years, this study found that FLO reduced toxicity as compared with FLP.
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Propagation, expansion, and multilineage differentiation of human somatic stem cells from dermal progenitors
G Bartsch,James J. Yoo,Paolo De Coppi,M. Minhaj Siddiqui,Gunter Schuch,Hans G. Pohl,Jasmin Fuhr,Laura Perin,Shay Soker,Anthony Atala +9 more
TL;DR: This study is the first to show potential growth of multipotential human MSC cell lines from a single cell that can be used for the engineering of tissues in vivo, and presents profound implications in the understanding of differentiation and development.
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In vivo administration of vascular endothelial growth factor (VEGF) and its antagonist, soluble neuropilin-1, predicts a role of VEGF in the progression of acute myeloid leukemia in vivo
Gunter Schuch,Marcelle Machluf,Georg Bartsch,Masashi Nomi,Henri Richard,Anthony Atala,Shay Soker +6 more
TL;DR: Results demonstrate that angiogenic factors such as VEGF promote AML progression in vivo and offer a potential treatment for AML, and a novel in vivo drug delivery model may be useful for testing the activities of other peptide antiangiogenic Factors.
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Pharmacogenetic Analyses of a Phase III Trial in Metastatic Gastroesophageal Adenocarcinoma With Fluorouracil and Leucovorin Plus Either Oxaliplatin or Cisplatin: A Study of the Arbeitsgemeinschaft Internistische Onkologie
Eray Goekkurt,Salah-Eddin Al-Batran,Jörg T. Hartmann,Ulrike Mogck,Gunter Schuch,Michael Kramer,Elke Jaeger,Carsten Bokemeyer,Gerhard Ehninger,Jan Stoehlmacher +9 more
TL;DR: Findings underline the hypothesis that germ-line polymorphisms may play an important role in individualizing chemotherapy in AGC and deserve further prospective evaluation inAGC patients.