G
Guo-Wei Wei
Researcher at Michigan State University
Publications - 328
Citations - 16850
Guo-Wei Wei is an academic researcher from Michigan State University. The author has contributed to research in topics: Persistent homology & Solvation. The author has an hindex of 63, co-authored 320 publications receiving 12992 citations. Previous affiliations of Guo-Wei Wei include University of British Columbia & University of Houston System.
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Characterizing SARS-CoV-2 mutations in the United States
TL;DR: The analysis suggests that female immune systems are more active than those of males in responding to SARS-CoV-2 infections, and identifies that one of the top mutations, 27964C>T-(S24L on ORF8, has an unusually strong gender dependence.
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Generative network complex for the automated generation of druglike molecules
TL;DR: In this paper, a generative network complex (GNC) was developed to generate new drug-like molecules based on the multi-property optimization via the gradient descent in the latent space of an autoencoder.
Journal ArticleDOI
Multiscale weighted colored graphs for protein flexibility and rigidity analysis.
David Bramer,Guo-Wei Wei +1 more
TL;DR: A paradigm-shifting geometric graph model, multiscale weighted colored graph (MWCG), is introduced to provide a new generation of computational algorithms to significantly change the current status of protein structural fluctuation analysis and provides perhaps the first reliable method for estimating protein flexibility and B-factors.
Journal ArticleDOI
Generalized flexibility-rigidity index.
TL;DR: In this paper, the structure of the classic Gaussian surface is utilized to construct a new type of rigidity index, which leads to a new class of rigidness densities with the classic GAussian surface as a special case.
Journal ArticleDOI
Generalized symmetric interpolating wavelets
TL;DR: A new class of biorthogonal wavelets-interpolating distributed approximating functional (DAF) wavelets are proposed as a powerful basis for scale-space functional analysis and approximation and efficient applications in computational science and engineering are explored.