R
Rui Wang
Researcher at Michigan State University
Publications - 76
Citations - 2744
Rui Wang is an academic researcher from Michigan State University. The author has contributed to research in topics: Biology & Computer science. The author has an hindex of 18, co-authored 59 publications receiving 1019 citations. Previous affiliations of Rui Wang include University of Western Ontario & City University of Hong Kong.
Papers
More filters
Journal ArticleDOI
Omicron Variant (B.1.1.529): Infectivity, Vaccine Breakthrough, and Antibody Resistance
TL;DR: An artificial intelligence model, which has been trained with tens of thousands of experimental data and extensively validated by experimental results on SARS-CoV-2, reveals that Omicron may be over 10 times more contagious than the original virus or about 2.8 times as infectious as the Delta variant.
Journal ArticleDOI
Mutations Strengthened SARS-CoV-2 Infectivity.
TL;DR: It is shown that most likely future mutations will make SARS-CoV-2 more infectious, and it is predicted that a few residues on the receptor-binding motif (RBM) have high chances to mutate into significantly more infectious COVID-19 strains.
Journal ArticleDOI
Mutations on COVID-19 diagnostic targets.
TL;DR: It is shown that SARS-CoV-2 has the most mutations on the targets of various nucleocapsid gene primers and probes, which have been widely used around the world to diagnose COVID-19, and that due to human immune response induced APOBEC mRNA (C >T) editing, diagnostic targets should also be selected to avoid cytidines.
Journal ArticleDOI
Vaccine-escape and fast-growing mutations in the United Kingdom, the United States, Singapore, Spain, India, and other COVID-19-devastated countries.
TL;DR: Wang et al. as mentioned in this paper carried out a large-scale study of 506,768 SARS-CoV-2 genome isolates from patients to identify many other rapidly growing mutations on the spike (S) protein receptor-binding domain (RBD).
Journal ArticleDOI
Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants.
TL;DR: Wang et al. as mentioned in this paper analyzed 45,494 complete SARS-CoV-2 geneome sequences in the world to understand their mutations and revealed that female immune systems are more active than those of males in responding to SARS CoV2 infections.