G
Guo-Wei Wei
Researcher at Michigan State University
Publications - 328
Citations - 16850
Guo-Wei Wei is an academic researcher from Michigan State University. The author has contributed to research in topics: Persistent homology & Solvation. The author has an hindex of 63, co-authored 320 publications receiving 12992 citations. Previous affiliations of Guo-Wei Wei include University of British Columbia & University of Houston System.
Papers
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Emerging Vaccine-Breakthrough SARS-CoV-2 Variants
TL;DR: It is illustrated that infectivity strengthening mutations were the main mechanism for viral evolution, while vaccine-escape mutations become a dominating viral evolutionary mechanism among highly vaccinated populations.
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Multiscale Gaussian network model (mGNM) and multiscale anisotropic network model (mANM)
TL;DR: In this article, a unified framework was proposed to construct generalized Kirchhoff matrices whose matrix inverse leads to gGNMs, whereas, the direct inverse of its diagonal elements gives rise to FRI method.
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Revealing the Threat of Emerging SARS-CoV-2 Mutations to Antibody Therapies.
TL;DR: In this article, a topology-based deep learning strategy was used to identify 606 non-degenerate RBD mutations and investigate their impacts on 16 mAbs in clinical trials.
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DG-GL: Differential geometry-based geometric learning of molecular datasets.
Duc Duy Nguyen,Guo-Wei Wei +1 more
TL;DR: Li et al. as discussed by the authors put forward a differential geometry-based geometric learning (DG-GL) hypothesis that the intrinsic physics of 3D molecular structures lies on a family of low-dimensional manifolds embedded in a high-dimensional data space.
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Temperature-modulated bioluminescence tomography
TL;DR: This paper proposes temperature-modulated bioluminescence tomography (TBT) to utilize the temperature dependence of biolumscence for superior BLT performance, and employs a focused ultrasound array to heat small volumes of interest (VOI) one at a time, and induce a detectable change in the optical signal on the body surface of a mouse.