G
Guy Patra
Researcher at University of Scranton
Publications - 10
Citations - 1034
Guy Patra is an academic researcher from University of Scranton. The author has contributed to research in topics: Bacillus anthracis & Brucella melitensis. The author has an hindex of 9, co-authored 10 publications receiving 999 citations.
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Journal ArticleDOI
The genome sequence of the facultative intracellular pathogen Brucella melitensis
Vito G. DelVecchio,Vinayak Kapatral,Rajendra J. Redkar,Guy Patra,Cesar V. Mujer,Tamara Los,Natalia Ivanova,Iain Anderson,Anamitra Bhattacharyya,Athanasios Lykidis,Gary Reznik,Lynn Jablonski,Niels Bent Larsen,Mark D'Souza,Axel Bernal,Mikhail Mazur,Eugene Goltsman,Eugene Selkov,Philip H. Elzer,Sue D. Hagius,David O'Callaghan,Jean-Jacques Letesson,Robert Haselkorn,Nikos C. Kyrpides,Ross Overbeek +24 more
TL;DR: The genome of B. melitensis strain 16M was sequenced and found to contain 3,294,935 bp distributed over two circular chromosomes encoding 3,197 ORFs, similar to other α-proteobacteria.
Journal ArticleDOI
Utilization of the rpoB gene as a specific chromosomal marker for real-time PCR detection of Bacillus anthracis.
Yuan Qi,Guy Patra,Xudong Liang,Leanne E. Williams,Sharon Rose,Rajendra J. Redkar,Vito G. DelVecchio +6 more
TL;DR: The therpoB-FRET assay could be used as a new chromosomal marker for rapid detection of B. anthracis because it can be performed on isolated DNA as well as crude vegetative cell lysates in less than 1 h.
Journal ArticleDOI
Proteomic profiling and identification of immunodominant spore antigens of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis
Vito G. DelVecchio,Joseph P. Connolly,Timothy G. Alefantis,Alexander Walz,Marian A. Quan,Guy Patra,John M. Ashton,Jessica T. Whittington,Ryan Chafin,Xudong Liang,Paul Grewal,Akbar S. Khan,Cesar V. Mujer +12 more
TL;DR: Comparative analysis of the spore immunome will be of significance for further nucleic acid- and immuno-based detection systems as well as next-generation vaccine development.
Journal ArticleDOI
The genome of Brucella melitensis.
TL;DR: The genome of Brucella melitensis strain 16M was sequenced and contained 3,294,931 bp distributed over two circular chromosomes that encoded genes such as those that encode for DNA replication, protein synthesis, core metabolism, and cell-wall biosynthesis.
Journal ArticleDOI
Comparative Secretome Analyses of Three Bacillus anthracis Strains with Variant Plasmid Contents
Janine M. Lamonica,Mary Ann Wagner,Michel Eschenbrenner,Leanne E. Williams,Tabbi L. Miller,Guy Patra,Vito G. DelVecchio +6 more
TL;DR: This study provides evidence that pXO2 is necessary for the maximal expression of the p XO1-encoded toxins lethal factor (LF), edema factor (EF), and protective antigen (PA) in B. anthracis strain RA3:00, and several newly identified putative virulence factors were observed.