G
György Vereb
Researcher at University of Debrecen
Publications - 156
Citations - 5122
György Vereb is an academic researcher from University of Debrecen. The author has contributed to research in topics: Förster resonance energy transfer & Receptor. The author has an hindex of 35, co-authored 148 publications receiving 4639 citations. Previous affiliations of György Vereb include University of California, San Francisco & Max Planck Society.
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Dynamic, yet structured: The cell membrane three decades after the Singer-Nicolson model
György Vereb,János Szöllosi,János Matkó,Péter Nagy,Tibor Farkas,László Vígh,László Mátyus,Thomas A. Waldmann,Sándor Damjanovich +8 more
TL;DR: This work pays tribute to the Singer–Nicolson model, honoring its basic features, “mosaicism” and “diffusion,” which predict the interspersion of proteins and lipids and their ability to undergo dynamic rearrangement via Brownian motion and proposes a new “dynamically structured mosaic model” based on quantitative data.
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Trastuzumab causes antibody-dependent cellular cytotoxicity–mediated growth inhibition of submacroscopic JIMT-1 breast cancer xenografts despite intrinsic drug resistance
Márk Barok,Jorma Isola,Zsuzsanna Pályi-Krekk,Péter Nagy,István Juhász,György Vereb,Päivikki Kauraniemi,Anita I Kapanen,Minna Tanner,János Szöllosi +9 more
TL;DR: In vitro ADCC reaction of human leukocytes was equally strong against breast cancer cells intrinsically sensitive or resistant to trastuzumab or even against a subline of JIMT-1 that was established from xenograft tumors growing despite trastzumab treatment.
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Lipid rafts and the local density of ErbB proteins influence the biological role of homo- and heteroassociations of ErbB2
Péter Nagy,Péter Nagy,György Vereb,Zsolt Sebestyén,Gábor Horváth,Stephen J. Lockett,Stephen J. Lockett,Sándor Damjanovich,John W. Park,Thomas M. Jovin,János Szöllősi +10 more
TL;DR: It is concluded that local densities of ErbB2 and ErbbB3, as well as the lipid environment profoundly influence the association properties and biological function of ErBB2.
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Temporally and spectrally resolved imaging microscopy of lanthanide chelates.
TL;DR: The combination of temporal and spectral resolution in fluorescence microscopy based on long-lived luminescent labels offers a dramatic increase in contrast and probe selectivity due to the suppression of scattered light and short-lived autofluorescence.
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Cholesterol-dependent clustering of IL-2Rα and its colocalization with HLA and CD48 on T lymphoma cells suggest their functional association with lipid rafts
György Vereb,János Matkó,György Vámosi,S. M. Ibrahim,E. Magyar,Sándor Varga,János Szöllősi,Attila Jenei,Rezső Gáspár,Thomas A. Waldmann,Sándor Damjanovich +10 more
TL;DR: The submicron clusters of IL-2Ralpha chains and their coclustering with HLA and CD48, presumably associated with lipid rafts, could underlie the efficiency of signaling in lymphoid cells.