H.A. Wilkins

TL;DR: The results support the hypothesis that the slow build-up of IgE to high levels and the early production of IgG4 antibodies, which may block IgE pathways, are responsible for delaying the development of protective immunity to S. haematobium.

TL;DR: The trend for reinfection to decrease with increasing age, after an allowance for variation in exposure, was highly significant and suggest that subjects in this area slowly acquire an increasing degree of immunity to the acquisition of S. haematobium infection which is effective in the absence of a mature egg laying infection.

TL;DR: It is suggested that subjects with elevated counts are less susceptible to reinfection but the mechanisms involved are not apparent, and at all levels of exposure children with high eosinophil counts were less likely to be reinfected than those with lower counts.

TL;DR: Preliminary observations suggest that age- and sex-related differences in the pattern of water contact may not fully account for the rate of acquisition of infection and its prevalence and that protective immunity in the epidemiology of schistosome infections is discussed.

TL;DR: The relationship between reinfection with Schistosoma haematobium and immunological parameters was studied in a group of Gambian children and the pattern of antigen recognition appeared unrelated to susceptibility to reinfections.