M
Matty Knight
Researcher at George Washington University
Publications - 60
Citations - 2117
Matty Knight is an academic researcher from George Washington University. The author has contributed to research in topics: Biomphalaria glabrata & Schistosoma mansoni. The author has an hindex of 31, co-authored 59 publications receiving 1982 citations. Previous affiliations of Matty Knight include University of the District of Columbia & National Institute for Medical Research.
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Journal ArticleDOI
Whole genome analysis of a schistosomiasis-transmitting freshwater snail.
Coen M. Adema,LaDeana W. Hillier,Catherine S. Jones,Eric S. Loker,Matty Knight,Matty Knight,Patrick Minx,Guilherme Oliveira,Nithya Raghavan,Andrew M. Shedlock,Laurence Rodrigues do Amaral,Halime D. Arican-Goktas,Juliana G Assis,Elio Hideo Baba,Olga Baron,Christopher J. Bayne,Utibe Bickham-Wright,Kyle K. Biggar,Michael S. Blouin,Bryony C. Bonning,Chris Botka,Joanna M. Bridger,Katherine M. Buckley,Sarah K. Buddenborg,Roberta Lima Caldeira,Julia B. Carleton,Omar dos Santos Carvalho,Maria G. Castillo,Iain W. Chalmers,Mikkel Christensens,Sandra W. Clifton,Céline Cosseau,Christine Coustau,Richard M. Cripps,Yesid Cuesta-Astroz,Scott F. Cummins,Leon di Stephano,Leon di Stephano,Nathalie Dinguirard,David Duval,Scott J. Emrich,Cédric Feschotte,René Feyereisen,Peter C. FitzGerald,Catrina Fronick,Lucinda Fulton,Richard Galinier,Sandra Grossi Gava,Michael E. Geusz,Kathrin K. Geyer,Gloria I. Giraldo-Calderón,Matheus de Souza Gomes,Michelle A. Gordy,Benjamin Gourbal,Christoph Grunau,Patrick C. Hanington,Karl F. Hoffmann,Daniel S.T. Hughes,Judith E. Humphries,Daniel J. Jackson,Liana K. Jannotti-Passos,Wander de Jesus Jeremias,Susan Jobling,Bishoy Kamel,Aurélie Kapusta,Satwant Kaur,Joris M. Koene,Andrea B. Kohn,Daniel Lawson,Scott P Lawton,Di Liang,Yanin Limpanont,Sijun Liu,Anne E. Lockyer,TyAnna L. Lovato,Fernanda Ludolf,Vince Magrini,Donald P. McManus,Mónica Medina,Milind Misra,Guillaume Mitta,Gerald M. Mkoji,Michael J. Montague,Cesar E. Montelongo,Leonid L. Moroz,Monica Munoz-Torres,Umar Niazi,Leslie R. Noble,Francislon Silva de Oliveira,Fabiano Sviatopolk-Mirsky Pais,Anthony T. Papenfuss,Anthony T. Papenfuss,Rob Peace,Janeth J. Pena,Emmanuel A. Pila,Titouan Quelais,Brian J. Raney,Jonathan P. Rast,David Rollinson,Izinara C Rosse,Bronwyn Rotgans,Edwin J. Routledge,Kathryn M. Ryan,Larissa L. S. Scholte,Kenneth B. Storey,Martin T. Swain,Jacob A. Tennessen,Chad Tomlinson,Damian L. Trujillo,Emanuela V. Volpi,Anthony J. Walker,Tianfang Wang,Ittiprasert Wannaporn,Wesley C. Warren,Xiao-Jun Wu,Timothy P. Yoshino,Mohammed Yusuf,Mohammed Yusuf,Si-Ming Zhang,Min Zhao,Richard K. Wilson +120 more
TL;DR: Parts of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata are described and several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis are identified.
Journal ArticleDOI
Genetics of Biomphalaria glabrata and its effect on the outcome of Schistosoma mansoni infection.
TL;DR: The importance of the snail's genetics in categorizing resistance in this complex invertebrate is discussed, some recent molecular evidence that may help to understand several of the problems that still remain, and some challenges lying ahead for investigators in this field.
Journal ArticleDOI
Comparative gene analysis of Biomphalaria glabrata hemocytes pre- and post-exposure to miracidia of Schistosoma mansoni.
Nithya Raghavan,André Miller,Malcolm J. Gardner,Peter C. FitzGerald,Anthony R. Kerlavage,David A. Johnston,Fred A. Lewis,Matty Knight +7 more
TL;DR: Investigation of transcription profiles in hemocytes of resistant snails pre- and post-exposure to Schistosoma mansoni suggested that parasite exposure caused an active metabolic response in the hemocytes, and identified transcripts showing 23-74% similarity to known reverse transcriptases (RT).
Journal ArticleDOI
The identification of markers segregating with resistance to Schistosoma mansoni infection in the snail Biomphalaria glabrata
Matty Knight,André Miller,Carolyn N. Patterson,Christopher G. Rowe,George S. Michaels,Daniel B. Carr,Charles S. Richards,Fred A. Lewis +7 more
TL;DR: DNA samples from individual F2 and F1 backcross progeny, segregating for either the resistant or susceptible phenotypes, were pooled (bulked segregant) to identify molecular markers associated with resistance to the parasite in the snail host.
Journal ArticleDOI
Isolation and characterisation of nucleic acids from the hydatid organisms, Echinococcus spp. (Cestoda).
TL;DR: The technique can now be used to analyse differential gene expression during development and differentiation of the hydatid organisms and to identify specific polypeptide antigens which may have potential as immunodiagnostic reagents.