H. C. Gooi

TL;DR: Evidence is described that the stage-specific embryonic antigen SSEA-1 involves the carbohydrate sequence Galβ1 → 4GlcNAc ↑1,3 Fucα, which is formed by α 1 → 3 fucosylation of blood group I or i antigens, respectively.

TL;DR: This article reports that both antibodies raised against the promyelomonocytic leukemia cell line HL60 recognize the carbohydrate structure 3‐fucosyl‐N‐acetyllactosamine with the following sequence: This structure is the same as that recognized by a hybridoma antibody against mouse teratocarcinoma cells (anti‐SSEA‐1) which recognizes an early embryonic antigen in the mouse.

TL;DR: Glycoproteins and oligosaccharides were extracted from meconium samples of group O neonates of secretor type by pronase digestion followed by precipitation in 67% aqueous ethanol and separated into Ii antigen enriched and depleted fractions by affinity chromatography.

TL;DR: A monoclonal antibody C14/1/46/10 showing preferential binding to membranes of human colorectal carcinomas over normal colon mucosae was obtained by immunization of mice with extra-nuclear membranes of a human colonic adenoma.

TL;DR: In this report the carbohydrate antigens expressed on the three oligosaccharide domains, core, backbone and peripheral, of mucin-type glycoproteins are briefly reviewed in the light of recent observations with monoclonal antibodies, raised that these carbohydrate structures are components of receptor systems for endogenous ligands.