H
H. Carsin
Researcher at Metz
Publications - 28
Citations - 3445
H. Carsin is an academic researcher from Metz. The author has contributed to research in topics: Procalcitonin & Antibacterial agent. The author has an hindex of 12, co-authored 28 publications receiving 3094 citations.
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Journal ArticleDOI
High serum procalcitonin concentrations in patients with sepsis and infection.
TL;DR: Serum concentrations seem to be correlated with the severity of microbial invasion, and Concentrations of a substance immunologically identical to procalcitonin are raised during septic conditions.
Journal ArticleDOI
Efficacy and tolerability of a cocktail of bacteriophages to treat burn wounds infected by Pseudomonas aeruginosa (PhagoBurn): a randomised, controlled, double-blind phase 1/2 trial.
P. Jault,Thomas Leclerc,Serge Jennes,Jean-Paul Pirnay,Yok-Ai Que,Grégory Resch,Anne-Françoise Rousseau,François Ravat,H. Carsin,Ronan Le Floch,Jean Vivien Schaal,Charles Soler,Cindy Fevre,Isabelle Arnaud,Laurent Bretaudeau,Jérôme Gabard +15 more
TL;DR: This randomised phase 1/2 trial aimed to compare the efficacy and tolerability of a cocktail of lytic anti-Pseudomonas aeruginosa bacteriophages with standard of care for patients with burns and found insufficient efficacy of PP1131.
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Long-term regeneration of human epidermis on third degree burns transplanted with autologous cultured epithelium grown on a fibrin matrix.
TL;DR: The use of fibrin matrices has been shown to have considerable advantages over plastic for the culture of skin cells for grafting and that it is now possible to generate and transplant enough cultured epithelium from a small skin biopsy to restore completely the epidermis of an adult human in 16 days as mentioned in this paper.
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Cultured epithelial autografts in extensive burn coverage of severely traumatized patients: a five year single-center experience with 30 patients
H. Carsin,P. Ainaud,Hervé Le Bever,J. M. Rives,Anne Lakhel,J. Stephanazzi,Frédéric Lambert,Julien Perrot +7 more
TL;DR: Epicel CEA successfully provided extensive, permanent burn coverage in severely traumatized patients, proving an important adjunct to achievement of a high survival rate in a patient population whose prognosis previously had been poor.
Journal ArticleDOI
Evolution and significance of circulating procalcitonin levels compared with IL-6, TNFα and endotoxin levels early after thermal injury
H. Carsin,Marcel Assicol,Fréderic Feger,Olivier Roy,Isabelle Pennacino,HervéLe Bever,P. Ainaud,Claude Bohuon +7 more
TL;DR: ProCT and IL6 are prognostic factors of mortality at the time of admission but less reliable than the clinical UBS (unit burn standard) score, and endotoxin and TNF alpha were undetectable, suggesting that the problem of the early gut bacterial translocation remains to be proven.