Silver nanoparticles as a new generation of antimicrobials.

The biology of interleukin-6.

Biological basis of the behavior of sick animals

The antibacterial action of silver is utilized in numerous consumer products and medical devices. Metallic silver, silver salts, and also silver nanoparticles are used for this purpose. The state of research on the effect of silver on bacteria, cells, and higher organisms is summarized. It can be concluded that the therapeutic window for silver is narrower than often assumed. However, the risks for humans and the environment are probably limited.

Silver as Antibacterial Agent: Ion, Nanoparticle, and Metal

Burns are one of the most common and devastating forms of trauma. Patients with serious thermal injury require immediate specialized care in order to minimize morbidity and mortality. Significant thermal injuries induce a state of immunosuppression that predisposes burn patients to infectious complications. A current summary of the classifications of burn wound infections, including their diagnosis, treatment, and prevention, is given. Early excision of the eschar has substantially decreased the incidence of invasive burn wound infection and secondary sepsis, but most deaths in severely burn-injured patients are still due to burn wound sepsis or complications due to inhalation injury. Burn patients are also at risk for developing sepsis secondary to pneumonia, catheter-related infections, and suppurative thrombophlebitis. The introduction of silver-impregnated devices (e.g., central lines and Foley urinary catheters) may reduce the incidence of nosocomial infections due to prolonged placement of these devices. Improved outcomes for severely burned patients have been attributed to medical advances in fluid resuscitation, nutritional support, pulmonary and burn wound care, and infection control practices.

Burn Wound Infections

A historical review of the use of silver in the treatment of burns. II. Renewed interest for silver.

Historical review of the use of silver in the treatment of burns. I. Early uses

Serum levels of interleukin-6 and acute phase responses.

Interleukin-6 and its relation to the humoral immune-response and clinical-parameters in burned patients

A review on the nonoperative removal of necrotic tissue from burn wounds

H.J. Klasen

Papers

A historical review of the use of silver in the treatment of burns. II. Renewed interest for silver.

Historical review of the use of silver in the treatment of burns. I. Early uses

Serum levels of interleukin-6 and acute phase responses.

Interleukin-6 and its relation to the humoral immune-response and clinical-parameters in burned patients

A review on the nonoperative removal of necrotic tissue from burn wounds