Showing papers in "The Lancet in 1987"

TL;DR: The observation of greatly increased postprandial plasma GLP-1 7-36 levels in patients with postgastrectomy dumping syndrome suggests that it may mediate the hyperinsulinaemia and reactive hypoglycaemia of this disorder.

TL;DR: Reduced fibrinolytic capacity due to increased plasma levels of the plasminogen activator inhibitor predisposes to reinfarction in a complex interplay with atherogenic factors, multiple coronary lesions, and compromised left ventricular function.

TL;DR: It is suggested that the effect of bradykinin is mediated by the release of nitric oxide from the endothelial cells, and thatNitric oxide release contributes to the non-adhesive properties of vascular endothelium.

TL;DR: Serum samples taken on admission from 79 patients with meningococcal meningitis, septicaemia, or both, were examined in a highly sensitive bioassay for tumour necrosis factor (TNF).

TL;DR: A concomitant increase in circulating monocytes bearing class II (HLA-DR) surface antigen suggested that the attacks induced during treatment were immunologically mediated, and IFN-gamma is unsuitable for treatment of MS.

TL;DR: Persistence of the association after allowance for other psychiatric illness and social background indicated that cannabis is an independent risk factor for schizophrenia.

TL;DR: No wonder you activities are, reading will be always needed, it is not only to fulfil the duties that you need to finish in deadline time.

TL;DR: Role du facteur dans la cicatrisation and dans les maladies (fibrose pulmonaire, sclerodermie, arthrites, atherosclerose)

TL;DR: EGFR status divides the ER- population into good and poor prognosis subgroups, and the presence of EGFR was the most important variable in the primary tumours for predicting relapse-free and overall survival.

TL;DR: Central obese individuals are at increased risk of CHD, independent of BMI, because of the relationship between central body fat distribution and SSF.

TL;DR: It is suggested that in both conditions there is a defect in the renal conversion of cortisol to cortisone by 11 beta-OHSD which results in high intrarenal cortisol levels, acting on type 1 mineralocorticoid receptors to cause sodium retention.

TL;DR: It is indicated that preterm babies mount a substantial stress response to surgery under anaesthesia with nitrous oxide and curare and that prevention of this response by fentanyl anaesthesia may be associated with an improved postoperative outcome.

TL;DR: In a population-based case-control study of infant mortality in two urban areas of southern Brazil, the type of milk in an infant's diet was found to be an important risk factor for deaths from diarrhoeal and respiratory infections and cow's and formula milk seemed to be equally hazardous.

TL;DR: Cough is a recognised side-effect of ACE inhibitors; the observation that cough challenge is changed by these drugs in normal subjects implies a role for ACE in the cough reflex, possibly by metabolism of substrates other than angiotensin I.

TL;DR: The high endogenous urease activity of Campylobacter pylori was exploited in a non-invasive test for the presence of this organism in the stomach and each positive breath test proved to be correlated with a positive culture or Warthin-Starry silver stain of a mucosal biopsy specimen, or both.

TL;DR: A new prognostic classification is simple to use and is superior to staging by the method of Dukes because it places twice as many patients into groups that provide a confident prediction of clinical outcome.

TL;DR: Investigation of time trends in mortality from cervical cancer in Denmark, Finland, Iceland, Norway, and Sweden since the early 1950s supports the conclusion that organised screening programmes have had a major impact on the reduction in mortality in the Nordic countries.

TL;DR: Specific control measures to reduce contamination and consumption of raw pork may reduce the incidence of YE infections.

TL;DR: There was a J-shaped relation, confined to those with evidence of ischaemic heart disease, between frequency of death from myocardial infarction and treatedDBP (phase V); the frequency was lowest at treated DBP of 85-90 mm Hg and rose with treated DBPs on either side of this range.

TL;DR: Of 22 patients undergoing repeat open-heart surgery through a previous median sternotomy wound 11 were randomised to receive the serine proteinase inhibitor aprotinin in high dosage, seven of whom received only the single unit of their own blood taken before cardiopulmonary bypass.

TL;DR: Patients with biliary obstruction due to malignant disease, and judged unfit for open operation, were randomised to have a biliary stent inserted either endoscopically via the papilla of Vater or percutaneously.

TL;DR: Age, late presentation, and rheumatoid factor seropositivity at presentation were poor prognostic factors, and the concept of "remission-inducing" drugs is fallacious.

TL;DR: Initial antibiotic therapy should always cover S pneumoniae and H influenzae, with Streptococcus pneumoniae, Haemophilus influensae, and influenza viruses those most frequently identified.

TL;DR: Findings suggest an important role for C pylori in duodenal ulcer relapse in the year after treatment, as well as a significant predictor of endoscopic relapse, in patients with endoscopically healed duodanal ulcers.

TL;DR: Brahms discusses the legal aspects of confidentiality and disclosure of HIV status to various third parties, and the legal liability and legal claims of HIV infected persons.

TL;DR: Long-term follow-up of the GISSI trial of intravenous streptokinase in acute myocardial infarction has shown persistence of the beneficial effect observed during the hospital phase, and SK thrombolysis should be considered among the recommended treatments of the acute phase.

TL;DR: The findings indicate that academic standards of care are compatible with widely varying patterns of practice and that medical care costs are not necessarily high in communities served largely by university hospitals, and emphasise the need for increased attention to the outcome and cost implications of differences in practice styles.

TL;DR: It is suggested that long-term UDCA might be a safe and effective treatment for PBC, but a randomised, controlled, double-blind trial is urgently needed.