H. Michael Wenz

TL;DR: The precision of the 310 capillary electrophoresis system, coupled with software developed for automated genotyping of alleles based on the use of an allelie ladder, allows for accurate genotypesing of STR loci.

TL;DR: Comparative sizing of known CEPH samples performed showed the usefulness of the system for genotyping with standard deviations of 0.24 nucleotide, or better, and the presence of denaturants and, more importantly, operation at 60 degrees C was mandatory for high-precision and high-resolution sizing operation.

TL;DR: In this article, a capillary tube with a charged inner surface for use in capillary electrophoresis and methods is described, where the tube is filled with an electrolyte solution containing 0.05-30 % weight/weight of a hydrophilic polymer which is characterized by a molecular weight of 20-5,000 kilodaltons, and a charge between 0.01 and 1.0 % as measured by the molar percent of charged monomer subunits to the total polymer subunits.

TL;DR: This study has begun to analyze mutations found in exon 7 of the p53 gene by SSCP using laser induced fluorescence capillary electrophoresis (LIF-CE), and should prove helpful in the rapid screening of target sequences that are known to bear a limited number of mutations.

TL;DR: In this paper, a 2.0 kbp region of the p53 gene containing exons 5--9 from seven cell lines reported in the literature to contain the majority of mutations reported for this gene was amplified by polymerase chain reaction (PCR).