C
Catherine D. O’Connell
Researcher at National Institute of Standards and Technology
Publications - 38
Citations - 1250
Catherine D. O’Connell is an academic researcher from National Institute of Standards and Technology. The author has contributed to research in topics: Gene & Point mutation. The author has an hindex of 18, co-authored 38 publications receiving 1205 citations.
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Journal ArticleDOI
Breakpoints of gross deletions coincide with non-B DNA conformations
Albino Bacolla,Adam Jaworski,Adam Jaworski,Jacquelynn E. Larson,John P. Jakupciak,Nadia Chuzhanova,Shaun S. Abeysinghe,Catherine D. O’Connell,David Neil Cooper,Robert D. Wells +9 more
TL;DR: It is concluded that alternative DNA conformations trigger genomic rearrangements through recombination-repair activities as well as predicted non-B DNA structures.
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ERV3, a full-length human endogenous provirus: chromosomal localization and evolutionary relationships.
TL;DR: A full-length human endogenous provirus termed ERV3 was isolated from a human fetal recombinant DNA library by low stringency hybridization with two probes: baboon endogenous virus LTR; and a pol-env subclone from the endogenous chimpanzee provirus, CH2.
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Bacteriophage MS2: Molecular Weight and Spatial Distribution of the Protein and RNA Components by Small-Angle Neutron Scattering and Virus Counting
TL;DR: A novel particle counting instrument, the integrated virus detection system (IVDS) is evaluated that has the potential to provide rapid quantitative physical characterization of unidentified viruses and phage.
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The nucleotide sequence of the env gene from the human provirus ERV3 and isolation and characterization of an ERV3-specific cDNA
TL;DR: Analysis of the nucleotide sequence revealed the presence of a long open reading frame of 1944 nucleotides that is capable of encoding a polypeptide that has characteristics of other retroviral glycoproteins and transmembrane proteins.
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Mitochondrial DNA as a cancer biomarker.
John P. Jakupciak,Wendy Wang,Maura E. Markowitz,Delphine Ally,Michael D. Coble,Sudhir Srivastava,Anirban Maitra,Peter E. Barker,David Sidransky,Catherine D. O’Connell +9 more
TL;DR: The development and implementation of a rapid and high-throughput sequencing protocol for the detection of sequence variants in mitochondrial DNA for clinical samples is described, confirming previously identified primary lung tumor changes and extended these findings in a small patient cohort.