H
H. Zhao
Researcher at Erasmus University Rotterdam
Publications - 3
Citations - 169
H. Zhao is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Fetus & Enzyme assay. The author has an hindex of 3, co-authored 3 publications receiving 152 citations.
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Journal ArticleDOI
A fluorimetric enzyme assay for the diagnosis of Morquio disease type A (MPS IV A)
O. P. van Diggelen,H. Zhao,Wim J. Kleijer,H.C. Janse,Ben J. H. M. Poorthuis,J.A. van Pelt,Johannis P. Kamerling,Hans Galjaard +7 more
TL;DR: A second incubation in the presence of excess beta-galactosidase is needed to avoid underestimation of galactose-6-sulphate sulphatase activity.
Journal ArticleDOI
Prenatal diagnosis of morquio disease type a using a simple fluorometric enzyme assay
TL;DR: Two enzyme tests indicated affected fetuses in two pregnancies and a non‐affected fetus in one, and the fluorometric assay is much more convenient than the conventional assay using radiolabelled, sulphated oligosaccharides.
Journal Article
Enzymatic diagnosis of Morquio A syndrome with a new fluorimetric substrate.
TL;DR: The synthetic 4-methylumbelliferyl-galactoside 6-sulphate (4Mu-Gal-6S) proved highly effective and sensitive in the postnatal, prenatal and retrospective diagnosis of Morquio A syndrome as compared to the commonly used radiolabelled substrate.