H
Hadi Danaee
Researcher at GlaxoSmithKline
Publications - 4
Citations - 238
Hadi Danaee is an academic researcher from GlaxoSmithKline. The author has contributed to research in topics: Endometrial cancer & Pharmacodynamics. The author has an hindex of 2, co-authored 4 publications receiving 57 citations.
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Journal ArticleDOI
Clinical Activity and Safety of the Anti-Programmed Death 1 Monoclonal Antibody Dostarlimab for Patients With Recurrent or Advanced Mismatch Repair-Deficient Endometrial Cancer: A Nonrandomized Phase 1 Clinical Trial
Ana Oaknin,Anna V. Tinker,Lucy Gilbert,Vanessa Samouëlian,Cara Mathews,Jubilee Brown,Maria-Pilar Barretina-Ginesta,Victor Moreno,Adriano Gravina,Cyril Abdeddaim,Susana Banerjee,W. Guo,Hadi Danaee,Ellie Im,Renaud Sabatier +14 more
TL;DR: Dostarlimab was associated with clinically meaningful and durable antitumor activity with an acceptable safety profile for patients with deficient mismatch repair endometrial cancers that have progressed after prior platinum-based chemotherapy.
Journal ArticleDOI
Preliminary safety, efficacy, and pharmacokinetic/pharmacodynamic characterization from GARNET, a phase I/II clinical trial of the anti–PD-1 monoclonal antibody, TSR-042, in patients with recurrent or advanced MSI-h and MSS endometrial cancer
Ana Oaknin,Linda R. Duska,R.J. Sullivan,Bhavana Pothuri,Susan Ellard,Charles A. Leath,V. Moreno,Rebecca Kristeleit,W. Guo,Hadi Danaee,Ellie Im,Lucy Gilbert +11 more
Journal ArticleDOI
Safety, antitumor activity, and pharmacokinetics of dostarlimab, an anti-PD-1, in patients with advanced solid tumors: a dose-escalation phase 1 trial.
Amita Patnaik,Glen J. Weiss,Drew W. Rasco,Lisa Blaydorn,Amy Mirabella,Murali Beeram,Wei Guo,Sharon Lu,Hadi Danaee,Kristen McEachern,Ellie Im,Jasgit C. Sachdev +11 more
TL;DR: In this article, the authors evaluated the PK, pharmacodynamics (PDy), and safety of dostarlimab monotherapy in adult patients with previously-treated advanced solid tumors who participated in parts 1 and 2A of the phase 1 GARNET study.