H
Hai-Yin Wu
Researcher at Nanjing Medical University
Publications - 49
Citations - 1710
Hai-Yin Wu is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Neuroprotection & Medicine. The author has an hindex of 18, co-authored 42 publications receiving 1312 citations.
Papers
More filters
Journal ArticleDOI
Treatment of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with PSD-95
Li Zhou,Fei Li,Hai-Bing Xu,Chun-Xia Luo,Hai-Yin Wu,Ming-Mei Zhu,Wei Lu,Xing Ji,Qi-Gang Zhou,Dong-Ya Zhu +9 more
TL;DR: This drug blocked the ischemia-induced nNOS–PSD-95 association selectively, had potent neuroprotective activity in vitro and ameliorated focal cerebral ischemic damage in mice and rats subjected to middle cerebral artery occlusion and reperfusion.
Journal ArticleDOI
Correction: Corrigendum: CREB-mediated synaptogenesis and neurogenesis is crucial for the role of 5-HT1a receptors in modulating anxiety behaviors
TL;DR: This Article contains an error in Figure 4A, where the LV-VP16-CREB-GFP + NAN-190 representative image is incorrect and the Figure legend is correct.
Journal ArticleDOI
Neuronal nitric oxide synthase alteration accounts for the role of 5-HT1A receptor in modulating anxiety-related behaviors.
Jing Zhang,Xin-Yan Huang,Min-Li Ye,Chun-Xia Luo,Hai-Yin Wu,Yao Hu,Qi-Gang Zhou,Dan-Lian Wu,Li-Juan Zhu,Dong-Ya Zhu +9 more
TL;DR: It is shown that 5-HT1AR-selective agonist 8-OH-DPAT and selective serotonin reuptake inhibitor (SSRI) fluoxetine downregulated hippocampal neuronal nitric oxide synthase (nNOS) expression, whereas NAN-190 upregulated hippocampusal nNOS expression, indicating that both hippocampal n NOS and CREB activity mediate the anxiolytic effects of 5- HT1AR agonists and SSRIs.
Journal ArticleDOI
Hippocampal Neuronal Nitric Oxide Synthase Mediates the Stress-Related Depressive Behaviors of Glucocorticoids by Downregulating Glucocorticoid Receptor
TL;DR: A role of hippocampal nNOS in regulating the behavioral effects of glucocorticoids is revealed, and it is reported here that hippocampal neuronal nitric oxide synthase (nNOS) is a crucial mediator.
Journal ArticleDOI
Hippocampal telomerase is involved in the modulation of depressive behaviors.
Qi-Gang Zhou,Yao Hu,Dan-Lian Wu,Li-Juan Zhu,Chen Chen,Xing Jin,Chun-Xia Luo,Hai-Yin Wu,Jing Zhang,Dong-Ya Zhu +9 more
TL;DR: The results suggest that hippocampal telomerase is involved in the modulation of depression-related behaviors, possibly by regulating adult neurogenesis.