Hai-Ying Jin

TL;DR: The results confirm the clinical usefulness of gene therapy for bone formation, using the BMP-2 gene combined with cationic liposomes as a vector and it is possible that the effects of administering the B MP-2 genes will be improved by specializing the microstructure of scaffold for gene therapy.

TL;DR: HGF supplementation through gene therapy may be an effective strategy for treating wounds, as it increases the regeneration of the dermis to allow for "scarless wound healing," according to its antifibrotic effect.

TL;DR: It is suggested that TYRP1 and DCT play an important role in suppressing TYR-mediated cytotoxicity in melanocytic cells without decreasing TYR expression and/or activity.

TL;DR: The intracellular vesicular trafficking in the melanosome biogenesis (melanogenesis) is reviewed with the incorporation of the authors' own experimental findings and it is suggested that tyrosinase is involved in lysosomal degradation after forming dopaquinone.

TL;DR: The findings indicate that the dominant-negative mutant of Rab7 impairs vesicular transport of tyrosinase and TRP-1, suggesting that the transport of these melanogenic proteins from the trans-Golgi network to maturing melanosomes requires passage through endosome-delineated compartments.