H
Haicen Yue
Researcher at New York University
Publications - 12
Citations - 174
Haicen Yue is an academic researcher from New York University. The author has contributed to research in topics: Protein subunit & G protein-coupled receptor. The author has an hindex of 5, co-authored 10 publications receiving 140 citations. Previous affiliations of Haicen Yue include University of California, San Diego & Courant Institute of Mathematical Sciences.
Papers
More filters
Journal ArticleDOI
Cellular memory in eukaryotic chemotaxis
Monica Skoge,Haicen Yue,Michael Erickstad,Albert Bae,Herbert Levine,Alex Groisman,William F. Loomis,Wouter-Jan Rappel +7 more
TL;DR: The study shows how spatiotemporal cues can guide cell migration over large distances by using microfluidics to expose cells to traveling waves of chemoattractant with varying periods and suggesting that chemotaxis to dynamic cues involves a coupling between adaptive directional sensing and bistable cellular memory.
Journal ArticleDOI
Correlation between oncogenic mutations and parameter sensitivity of the apoptosis pathway model.
Jia Chen,Haicen Yue,Qi Ouyang +2 more
TL;DR: This result shows that the position of the bifurcation point is a better measure of the functionality of a biological network than gene expression levels of certain key proteins, and demonstrates the suitability of applying systems-level analysis to biological networks as opposed to studying genes or proteins in isolation.
Journal ArticleDOI
Inferring single-cell behaviour from large-scale epithelial sheet migration patterns
TL;DR: In this study, insight into the mechanisms behind collective migration is provided by studying cell migration in a spreading monolayer of epithelial MCF10A cells using particle image velocimetry and finds that cell groups have features of motion that span multiple length scales.
Journal ArticleDOI
Minimal Network Topologies for Signal Processing during Collective Cell Chemotaxis.
TL;DR: Simulations of a stochastic biochemical model of border cell chemotaxis of the Drosophila egg chamber show that the qualitative selection procedure accurately determines which topologies are consistent with the experiment, and the model fits for all six proposed topologies.
Posted ContentDOI
PI3K inhibition reverses migratory direction of single cells but not cell groups in electric field
Yaohui Sun,Haicen Yue,Calina Copos,Kevin Zhu,Y Zhang,X Gao,B Reid,Francis Lin,Min Zhao,Alex Mogilner +9 more
TL;DR: The results are most consistent with the hypothesis, supported by the computational model, that cells inside and at the edge of the groups interpret directional signals differently, and that a tug-of-war between the edge and inner cells directs the cell groups.