Hajime Uno

TL;DR: The observed anatomical distribution of damage, and the cellular features of the damage agree with that observed in instances of GC-induced toxicity in the rodent hippocampus, and of stress-inducedoxicity in the primate hippocampus, suggesting that sustained GC exposure (whether due to stress, Cushings syndrome or exogenous administration) might damage the human hippocampus.

TL;DR: A simple C-statistic is presented which consistently estimates a conventional concordance measure which is free of censoring and results from numerical studies suggest that the new procedure performs well in finite sample.

TL;DR: The relationships between SCNA levels, tumor mutations, and cancer hallmarks are examined to find that two hallmarks of cancer, cell proliferation and immune evasion, are predicted by distinct types of aneuploidy that likely act through distinct mechanisms.

TL;DR: Critical concerns regarding this conventional practice of quantifying the underlying differences between groups with respect to a time-to-event end point are summarized and various well-known alternatives are discussed.

TL;DR: A poor initial hematopoietic response to darbepoetin alfa was associated with an increased subsequent risk of death or cardiovascular events as doses were escalated to meet target hemoglobin levels.