H
Hala Gali-Muhtasib
Researcher at American University of Beirut
Publications - 122
Citations - 6367
Hala Gali-Muhtasib is an academic researcher from American University of Beirut. The author has contributed to research in topics: Apoptosis & Thymoquinone. The author has an hindex of 38, co-authored 116 publications receiving 5523 citations. Previous affiliations of Hala Gali-Muhtasib include Lebanese University & American University.
Papers
More filters
Journal ArticleDOI
What made sesquiterpene lactones reach cancer clinical trials
TL;DR: This review focuses on the chemical and biological properties of SLs that lead to enhanced anticancer and anti-inflammatory effects.
Journal ArticleDOI
Thymoquinone: a promising anti-cancer drug from natural sources.
TL;DR: Thymoquinone is the bioactive constituent of the volatile oil of black seed that has been shown to exert anti-neoplastic and anti-inflammatory effects and the combination of TQ with clinically used anti-cancer drugs has led to improvements in their therapeutic index and prevents non-tumor tissues from sustaining chemotherapy-induced damage.
Journal Article
Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism.
Hala Gali-Muhtasib,Mona Diab-Assaf,Carsten Boltze,Josianne Al-Hmaira,Roland Hartig,Albert Roessner,Regine Schneider-Stock +6 more
TL;DR: In this article, the effects of thymoquinone (TQ) against HCT-116 human colon cancer cells and attempted to identify its potential molecular mechanisms of action.
Journal ArticleDOI
Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism.
Hala Gali-Muhtasib,Mona Diab-Assaf,Carsten Boltze,Josianne Al-Hmaira,Roland Hartig,Albert Roessner,Regine Schneider-Stock +6 more
TL;DR: The results indicate that TQ is antineoplastic and pro-apoptotic against colon cancer cell line HCT116, and the potential for using the agent TQ for the treatment of colon cancer is supported.
Journal ArticleDOI
Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling
Nahed El-Najjar,Nahed El-Najjar,Manal Chatila,Hiba A. Moukadem,Heikki Vuorela,Matthias Ocker,Muktheshwar Gandesiri,Regine Schneider-Stock,Hala Gali-Muhtasib +8 more
TL;DR: Evidence is presented linking the pro-oxidant effects of TQ with its apoptotic effects in colon cancer and prove a protective role of MAPK.