H
Hana Vaisocherová
Researcher at Academy of Sciences of the Czech Republic
Publications - 32
Citations - 2833
Hana Vaisocherová is an academic researcher from Academy of Sciences of the Czech Republic. The author has contributed to research in topics: Surface plasmon resonance & Biosensor. The author has an hindex of 22, co-authored 32 publications receiving 2608 citations. Previous affiliations of Hana Vaisocherová include Charles University in Prague & Seattle University.
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Journal ArticleDOI
Ultralow Fouling and Functionalizable Surface Chemistry Based on a Zwitterionic Polymer Enabling Sensitive and Specific Protein Detection in Undiluted Blood Plasma
Hana Vaisocherová,Wei Yang,Zheng Zhang,Zhiqiang Cao,Gang Cheng,Marek Piliarik,Jiří Homola,Shaoyi Jiang +7 more
TL;DR: A zwitterionic poly(carboxybetaine acrylamide) (polyCBAA) biomimetic material was employed to create a unique biorecognition coating with an ultralow fouling background, enabling the sensitive and specific detection of proteins in blood plasma.
Journal ArticleDOI
Nonfouling Behavior of Polycarboxybetaine-Grafted Surfaces: Structural and Environmental Effects
TL;DR: Results show that most of these surfaces exhibit high protein resistance in a wide range of ionic strengths and are more effective than zwitterionic self-assembled monolayers.
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Film Thickness Dependence of Protein Adsorption from Blood Serum and Plasma onto Poly(sulfobetaine)-Grafted Surfaces
TL;DR: Results show that the surface with 62 nm polySBMA brushes presents the best nonfouling character in 100% blood serum and plasma although all of these surfaces are highly resistant to nonspecific protein adsorption from single fibrinogen and lysozyme solutions.
Journal ArticleDOI
Multi-analyte surface plasmon resonance biosensing.
TL;DR: This paper reports application of a recently developed multichannel SPR sensor based on spectroscopy of surface plasmons and wavelength division multiplexing of sensing channels to multi-analyte detection.
Journal ArticleDOI
Functionalizable surface platform with reduced nonspecific protein adsorption from full blood plasma—Material selection and protein immobilization optimization
Hana Vaisocherová,Zheng Zhang,Wei Yang,Zhiqiang Cao,Gang Cheng,Allen Taylor,Marek Piliarik,Jirrr Homola,Shaoyi Jiang +8 more
TL;DR: In this article, the effect of the spacer length between the two charged groups on the nonfouling properties of zwitterionic poly(carboxybetaine acrylamide) (polyCBAA) was studied in blood plasma and serum.