H
Hande Gurer-Orhan
Researcher at Ege University
Publications - 32
Citations - 2946
Hande Gurer-Orhan is an academic researcher from Ege University. The author has contributed to research in topics: Oxidative stress & Antioxidant. The author has an hindex of 17, co-authored 29 publications receiving 2527 citations. Previous affiliations of Hande Gurer-Orhan include Missouri University of Science and Technology & VU University Amsterdam.
Papers
More filters
Journal ArticleDOI
Toxic Metals and Oxidative Stress Part I: Mechanisms Involved in Me-tal induced Oxidative Damage
TL;DR: It is suggested that metal-induced oxidative stress in cells can be partially responsible for the toxic effects of heavy metals, suggesting the importance of using antioxidants in heavy metal poisoning.
Journal ArticleDOI
Correlation between clinical indicators of lead poisoning and oxidative stress parameters in controls and lead-exposed workers
TL;DR: Analysis of blood of battery plant workers and control subjects indicates that ALAD can serve as a valuable biomarker of oxidative stress in lead-exposed hematological system as well as being a biochemical indicator of lead exposure.
Journal ArticleDOI
Detection of Reactive Oxygen and Nitrogen Species by Electron Paramagnetic Resonance (EPR) Technique
TL;DR: Current EPR (Electron Paramagnetic Resonance) spectroscopy methods for measuring ROS, RNS, and their secondary products are reviewed, and the strengths and limitations of specific methodological approaches are discussed.
Journal ArticleDOI
Preventive effect of aminoguanidine compared to vitamin E and C on cisplatin-induced nephrotoxicity in rats.
TL;DR: The nephrotoxicity was confirmed biochemically by significant elevation of serum urea and creatinine levels and both vitamin C-E combination and aminoguanidine prevented the increase in serum Urea levels according to the cisplatin group.
Journal ArticleDOI
Misincorporation of Free m -tyrosine into Cellular Proteins: A Potential Cytotoxic Mechanism for Oxidized Amino Acids
Hande Gurer-Orhan,Nuran Ercal,Suneetha Mare,Subramaniam Pennathur,Hilmi Orhan,Jay W. Heinecke +5 more
TL;DR: It is demonstrated that free m-tyrosine is toxic to cultured CHO (Chinese-hamster ovary) cells and misincorporation of free oxidized amino acids during protein synthesis may represent an alternative mechanism for oxidative stress and tissue injury during aging and disease.