H
Hannah Degroote
Researcher at Katholieke Universiteit Leuven
Publications - 1
Citations - 40
Hannah Degroote is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Fungal protein & Protein structure. The author has an hindex of 1, co-authored 1 publications receiving 28 citations.
Papers
More filters
Journal ArticleDOI
Protein interaction evolution from promiscuity to specificity with reduced flexibility in an increasingly complex network.
Tareq Alhindi,Zhicheng Zhang,Philip Ruelens,Heleen Coenen,Hannah Degroote,Nunzio Iraci,Koen Geuten +6 more
TL;DR: These findings illustrate that protein interaction evolution occurs at the level of conformational dynamics, when the binding mechanism concerns an induced fit or conformational selection, and can evolve towards increased specificity with reduced flexibility when the complexity of the protein interaction network requires specificity.