Hans Jürgen Menzel

TL;DR: Comparison of the average excesses by a method of repeated sampling with random permutations revealed no significant difference in effects among populations, indicating that a given apo E allele acts in a relatively uniform manner in different populations despite differences in genetic background and environmental factors.

TL;DR: This work determined the effects of the apo(a) isoforms on total cholesterol, high-density lipo-protein (HDL)-cholesterol, lipoprotein(a), and triglyceride levels in a sample of 473 unrelated Tyrolean adults, finding the strongest effect of a single polymorphic gene on plasma lipid and lipop protein levels reported so far.

TL;DR: The data suggest that in ABL, the assembly of apoB-containing lipoproteins is defective and that apOB-100 may be secreted without its full lipid complement when complexed with apo(a).

TL;DR: It is estimated that genetic variation at the apo A-IV gene locus accounts for 11% of the total variability in HDL-cholesterol levels in Tiroleans, and may serve to enrich, the limited knowledge of the role of apo C-IV in lipid metabolism.

TL;DR: It is concluded that the +93 C/T polymorphism is the second known intragenic apo(a) polymorphism which affects Lp( a) levels directly in vivo and that allelic associations may mask the effect of a mutation.