H
Hans-Jürgen Wester
Researcher at Technische Universität München
Publications - 378
Citations - 24749
Hans-Jürgen Wester is an academic researcher from Technische Universität München. The author has contributed to research in topics: Positron emission tomography & Prostate cancer. The author has an hindex of 76, co-authored 356 publications receiving 21247 citations. Previous affiliations of Hans-Jürgen Wester include University of Hamburg & Ludwig Maximilian University of Munich.
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Journal ArticleDOI
Evaluation of Hybrid 68Ga-PSMA Ligand PET/CT in 248 Patients with Biochemical Recurrence After Radical Prostatectomy
Matthias Eiber,Tobias Maurer,Michael Souvatzoglou,Ambros J. Beer,Alexander Ruffani,Bernhard Haller,Frank Philipp Graner,Hubert Kübler,Uwe Haberhorn,Michael Eisenhut,Hans-Jürgen Wester,Jürgen E. Gschwend,Markus Schwaiger +12 more
TL;DR: In this paper, the authors investigated the detection rate of 68Ga-PSMA PET/CT in patients with biochemical recurrence after radical prostatectomy and found that the detection rates were correlated with PSA level and PSA kinetics.
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Diagnostic Efficacy of (68)Gallium-PSMA Positron Emission Tomography Compared to Conventional Imaging for Lymph Node Staging of 130 Consecutive Patients with Intermediate to High Risk Prostate Cancer
Tobias Maurer,Jürgen E. Gschwend,Isabel Rauscher,Michael Souvatzoglou,Bernhard Haller,Gregor Weirich,Hans-Jürgen Wester,Matthias Heck,Hubert Kübler,Ambros J. Beer,Ambros J. Beer,Markus Schwaiger,Matthias Eiber +12 more
TL;DR: In patients with intermediate to high risk prostate cancer preoperative lymph node staging with (68)Ga-PSMA-PET proved to be superior to standard routine imaging, and has the potential to replace current standard imaging for this indication if confirmed by prospective studies.
Journal Article
Noninvasive Imaging of αvβ3 Integrin Expression Using 18F-labeled RGD-containing Glycopeptide and Positron Emission Tomography
Roland Haubner,Hans-Jürgen Wester,Wolfgang A. Weber,Christian Mang,Sibylle Ziegler,Simon L. Goodman,Reingard Senekowitsch-Schmidtke,Horst Kessler,Markus Schwaiger +8 more
TL;DR: First imaging results using a small animal positron emission tomograph suggest that this compound is suitable for noninvasive determination of the α v β 3 integrin status and therapy monitoring.
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Noninvasive Visualization of the Activated αvβ3 Integrin in Cancer Patients by Positron Emission Tomography and [18F]Galacto-RGD
Roland Haubner,Wolfgang A. Weber,Ambros J. Beer,Eugenija Vabuliene,Daniel Reim,Mario Sarbia,Karl-Friedrich Becker,Michael Goebel,Rüdiger Hein,Hans-Jürgen Wester,Horst Kessler,Markus Schwaiger +11 more
TL;DR: Molecular imaging with [18F]Galacto-RGD and PET can provide important information for planning and monitoring anti-angiogenic therapies targeting the αvβ3 integrins and can reveal the involvement and role of this integrin in metastatic and angiogenic processes in various diseases.
Journal Article
Glycosylated RGD-Containing Peptides: Tracer for Tumor Targeting and Angiogenesis Imaging with Improved Biokinetics
Roland Haubner,Hans-Jürgen Wester,Fred Burkhart,Reingard Senekowitsch-Schmidtke,Wolfgang A. Weber,Simon L. Goodman,Horst Kessler,Markus Schwaiger +7 more
TL;DR: The synthesis and biological evaluation of the first glycosylated RGD-containing peptide (RGD-peptide) for the noninvasive imaging of alpha(v)beta3 expression demonstrates that the introduction of a sugar moiety improves the pharmakokinetic behavior of the peptide.