Hansje H Bredero-Boelhouwer

TL;DR: OSAS is highly prevalent in syndromic craniosynostosis and there is some natural improvement, mainly during the first 3 years of life and least in children with Apert or Crouzon/Pfeiffer syndrome.

TL;DR: OSAS in Treacher Collins patients is an important problem so all patients should be screened for OSAS by polysomnography and non-invasive ventilation (continuous positive airway pressure or bilevel positive airways pressure) or tracheotomy should be considered as a treatment modality.

TL;DR: This study evaluated the accuracy of established obstructive sleep apnea syndrome questionnaires based on presenting symptoms and complaints as screening tools for OSAS in Treacher‐Collins syndrome (TCS).

TL;DR: A triage system was trial at the Dutch Craniofacial Center to increase efficiency and to ensure patients enter the correct clinical pathway earlier, and none of the patients triaged as nonsynostotic deformity on the flowcharts were found to be true craniosynostosis after clinical assessment by the CNP.

TL;DR: Since the clinical consequences can be severe and surgical intervention is possible, skull growth and signs and symptoms of increased ICP should be monitored in both neuronopathic and non-neuronopathic patients with MPS.