H
Hao He
Researcher at Tulane University
Publications - 24
Citations - 484
Hao He is an academic researcher from Tulane University. The author has contributed to research in topics: Genome-wide association study & Candidate gene. The author has an hindex of 11, co-authored 24 publications receiving 397 citations.
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Journal ArticleDOI
Meta-analysis of genome-wide association data identifies novel susceptibility loci for obesity
Yu-Fang Pei,Lei Zhang,Lei Zhang,Yong-Jun Liu,Jian Li,Hui Shen,Yao-Zhong Liu,Qing Tian,Hao He,Shuyan Wu,Shu Ran,Yingying Han,Rong Hai,Yong Lin,Jingying Zhu,Xue-Zhen Zhu,Christopher J. Papasian,Hong-Wen Deng,Hong-Wen Deng +18 more
TL;DR: A novel gene NLK (nemo-like kinase) in 17q11 that was significantly associated with FBM adjusted by LBM and rs6567160 may exert pleiotropic effects to both FBM and LBM are identified.
Journal ArticleDOI
Replication of 6 Obesity Genes in a Meta-Analysis of Genome-Wide Association Studies from Diverse Ancestries
Li-Jun Tan,Hu Zhu,Hao He,Ke-Hao Wu,Jian Li,Xiang-Ding Chen,Ji-Gang Zhang,Hui Shen,Qing Tian,Marie Krousel-Wood,Christopher J. Papasian,Claude Bouchard,Louis Pérusse,Hong-Wen Deng,Hong-Wen Deng +14 more
TL;DR: The role of FTO, CTNNBL1, LEPR and PPARG in obesity predisposition is confirmed and sex and ethnic differences in genetic susceptibility across populations of diverse ancestries may contribute to a more targeted prevention and customized treatment of obesity.
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Network-based proteomic analysis for postmenopausal osteoporosis in Caucasian females.
Lan Zhang,Yao-Zhong Liu,Yong Zeng,Yong Zeng,Wei Zhu,Ying-Chun Zhao,Ji-Gang Zhang,Jia-Qiang Zhu,Hao He,Hui Shen,Qing Tian,Fei-Yan Deng,Fei-Yan Deng,Christopher J. Papasian,Hong-Wen Deng,Hong-Wen Deng +15 more
TL;DR: Protein expression profiling of peripheral blood monocytes in 42 postmenopausal women with discordant bone mineral density (BMD) levels and gene set enrichment analysis revealed that two significantly enriched gene sets may be involved in post menopausal BMD variation by regulating pro‐inflammatory cytokines activities.
Journal ArticleDOI
Integrative Analysis of Genomics and Transcriptome Data to Identify Potential Functional Genes of BMDs in Females.
Yuan Cheng Chen,Yan-Fang Guo,Hao He,Xu Lin,Xia Fang Wang,Rou Zhou,Wen Ting Li,Dao Yan Pan,Jie Shen,Hong-Wen Deng,Hong-Wen Deng +10 more
TL;DR: A module and several genes in the model are highlighted as playing important roles in the regulation of bone mass in females, which may yield novel insights into the genetic basis of osteoporosis.
Journal ArticleDOI
Comparison of statistical methods for subnetwork detection in the integration of gene expression and protein interaction network.
TL;DR: jActiveModules, PinnacleZ and WMAXC performed well in identifying subnetwork with relative high precision and recall, and BioNet performed very well only in precision.