C
Christopher J. Papasian
Researcher at University of Missouri–Kansas City
Publications - 120
Citations - 5698
Christopher J. Papasian is an academic researcher from University of Missouri–Kansas City. The author has contributed to research in topics: Genome-wide association study & Single-nucleotide polymorphism. The author has an hindex of 43, co-authored 119 publications receiving 5154 citations. Previous affiliations of Christopher J. Papasian include University of Missouri & University of Shanghai for Science and Technology.
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Journal ArticleDOI
Correlation of obesity and osteoporosis: effect of fat mass on the determination of osteoporosis.
Lan-Juan Zhao,Hui Jiang,Christopher J. Papasian,Dev Maulik,Betty M. Drees,James A. Hamilton,Hong-Wen Deng,Hong-Wen Deng,Hong-Wen Deng +8 more
TL;DR: It is unclear whether fat has beneficial effects on bone, and it is anticipated that this will be an active and fruitful focus of research in the coming years.
Journal ArticleDOI
Genome-wide Copy-Number-Variation Study Identified a Susceptibility Gene, UGT2B17, for Osteoporosis
Tie-Lin Yang,Xiang Ding Chen,Yan Guo,Shu Feng Lei,Jin Tang Wang,Qi Zhou,Feng Pan,Yuan Chen,Zhi Xin Zhang,Shan-Shan Dong,Xiang Hong Xu,Han Yan,Xiao-Gang Liu,Chuan Qiu,Xue Zhen Zhu,Teng Chen,Meng Li,Hong Zhang,Liang Zhang,Betty M. Drees,James J. Hamilton,Christopher J. Papasian,Robert R. Recker,Xiaoping Song,Jing Cheng,Hong-Wen Deng,Hong-Wen Deng,Hong-Wen Deng +27 more
TL;DR: The association between CNV of UGT2B17 and OF was successfully replicated in an independent Chinese sample containing 399 cases with hip OF and 400 controls, suggesting the important contribution of CNV to the pathogenesis of osteoporosis.
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Genome-wide Association and Follow-Up Replication Studies Identified ADAMTS18 and TGFBR3 as Bone Mass Candidate Genes in Different Ethnic Groups
Dong Hai Xiong,Xiao-Gang Liu,Yan-Fang Guo,Li Jun Tan,Liang Wang,Bao Yong Sha,Zi Hui Tang,Feng Pan,Tie-Lin Yang,Xiang Ding Chen,Shu Feng Lei,Laura M. Yerges,Xue Zen Zhu,Victor W. Wheeler,Alan L. Patrick,C. H. Bunker,Yan Guo,Han Yan,Yu-Fang Pei,Yin Pin Zhang,Shawn Levy,Christopher J. Papasian,Peng Xiao,Y. Wang Lundberg,Robert R. Recker,Yao Zhong Liu,Yong Jun Liu,Joseph M. Zmuda,Hong-Wen Deng +28 more
TL;DR: The evidence supports that ADAMTS18 and TGFBR3 might underlie BMD determination in the major human ethnic groups.
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Connections between the human gut microbiome and gestational diabetes mellitus.
Ya-Shu Kuang,Jinhua Lu,Shenghui Li,Junhua Li,Ming-Yang Yuan,Jian-Rong He,Nian-Nian Chen,Wan-Qing Xiao,Songying Shen,Lan Qiu,Ying-Fang Wu,Cui-Yue Hu,Yan-Yan Wu,Weidong Li,Qiao-Zhu Chen,Hong-Wen Deng,Hong-Wen Deng,Christopher J. Papasian,Huimin Xia,Xiu Qiu +19 more
TL;DR: Novel relationships between the gut microbiome and GDM status are discovered and it is suggested that changes in microbial composition may potentially be used to identify individuals at risk for GDM.
Journal ArticleDOI
Genome-wide association scans identified CTNNBL1 as a novel gene for obesity
Yong Jun Liu,Xiao-Gang Liu,Xiao-Gang Liu,Liang Wang,Liang Wang,Christian Dina,Han Yan,Han Yan,Jianfeng Liu,Shawn Levy,Christopher J. Papasian,Betty M. Drees,James J. Hamilton,David Meyre,Jérôme Delplanque,Yu-Fang Pei,Lei Zhang,Robert R. Recker,Philippe Froguel,Philippe Froguel,Hong-Wen Deng +20 more
TL;DR: A genome-wide association scan for obesity is performed by examining approximately 500 000 single-nucleotide polymorphisms (SNPs) in a sample of 1000 unrelated US Caucasians to identify a novel gene, CTNNBL1, which has multiple SNPs associated with body mass index (BMI) and fat mass.