H
Haoming Lin
Researcher at Sun Yat-sen University
Publications - 3
Citations - 357
Haoming Lin is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Programmed cell death & Apoptosis. The author has an hindex of 2, co-authored 3 publications receiving 115 citations.
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Journal ArticleDOI
RSL3 Drives Ferroptosis Through GPX4 Inactivation and ROS Production in Colorectal Cancer.
Xinbing Sui,Ruonan Zhang,Shuiping Liu,Ting Duan,Lijuan Zhai,Mingming Zhang,Xuemeng Han,Yu Xiang,Xingxing Huang,Haoming Lin,Tian Xie +10 more
TL;DR: It is shown that ferroptosis inducer RSL3 initiated cell death and ROS accumulation in HCT116, LoVo, and HT29 CRC cells over a 24 h time course, and that ROS levels and transferrin expression were elevated in CRC cells treated with R SL3 accompanied by a decrease in the expression of glutathione peroxidase 4 (GPX4), indicating an iron-dependent cell death, ferroPTosis.
Journal ArticleDOI
PCDH17 increases the sensitivity of colorectal cancer to 5-fluorouracil treatment by inducing apoptosis and autophagic cell death.
Shuiping Liu,Haoming Lin,Da Wang,Qiang Li,Hong Luo,Guo-Xiong Li,Xiaohui Chen,Yongqiang Li,Peng Chen,Bingtao Zhai,Wengang Wang,Ruonan Zhang,Bi Chen,Mingming Zhang,Xuemeng Han,Qiujie Li,Liuxi Chen,Ying Liu,Xiaying Chen,Guohua Li,Yu Xiang,Ting Duan,Jiao Feng,Lou Jianshu,Xingxing Huang,Qin Zhang,Ting Pan,Lili Yan,Ting Jin,Wenzheng Zhang,Lvjia Zhuo,Yitian Sun,Tian Xie,Xinbing Sui,Xinbing Sui +34 more
TL;DR: It is suggested for the first time that PCDH17 increases the sensitivity of CRC to 5-FU treatment by inducing apoptosis and JNK-dependent autophagic cell death.
Journal ArticleDOI
Molecular profiling analysis for colorectal cancer patients with Pi-Xu or Shi-Re syndrome.
TL;DR: The results suggest that Shi-Re ZHENG conditions may contribute to poor overall survival in patients with colorectal cancer.