T
Ting Duan
Researcher at Hangzhou Normal University
Publications - 26
Citations - 1051
Ting Duan is an academic researcher from Hangzhou Normal University. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 7, co-authored 18 publications receiving 293 citations.
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Journal ArticleDOI
RSL3 Drives Ferroptosis Through GPX4 Inactivation and ROS Production in Colorectal Cancer.
Xinbing Sui,Ruonan Zhang,Shuiping Liu,Ting Duan,Lijuan Zhai,Mingming Zhang,Xuemeng Han,Yu Xiang,Xingxing Huang,Haoming Lin,Tian Xie +10 more
TL;DR: It is shown that ferroptosis inducer RSL3 initiated cell death and ROS accumulation in HCT116, LoVo, and HT29 CRC cells over a 24 h time course, and that ROS levels and transferrin expression were elevated in CRC cells treated with R SL3 accompanied by a decrease in the expression of glutathione peroxidase 4 (GPX4), indicating an iron-dependent cell death, ferroPTosis.
Journal ArticleDOI
Combinative treatment of β-elemene and cetuximab is sensitive to KRAS mutant colorectal cancer cells by inducing ferroptosis and inhibiting epithelial-mesenchymal transformation.
Peng Chen,Peng Chen,Xuejie Li,Ruonan Zhang,Shuiping Liu,Yu Xiang,Mingming Zhang,Xiaying Chen,Ting Pan,Lili Yan,Jiao Feng,Ting Duan,Da Wang,Bi Chen,Ting Jin,Wengang Wang,Liuxi Chen,Xingxing Huang,Wenzheng Zhang,Yitian Sun,Guohua Li,Lingpan Kong,Xiaohui Chen,Yongqiang Li,Zuyi Yang,Qin Zhang,Lvjia Zhuo,Xinbing Sui,Tian Xie,Tian Xie +29 more
TL;DR: The data for the first time suggest that the natural product β-elemene is a new ferroptosis inducer and combinative treatment of β- elemene and cetuximab is sensitive to KRAS mutant CRC cells by inducing ferroPTosis and inhibiting EMT, which will hopefully provide a prospective strategy for CRC patients with RAS mutations.
Journal ArticleDOI
Erianin, a novel dibenzyl compound in Dendrobium extract, inhibits lung cancer cell growth and migration via calcium/calmodulin-dependent ferroptosis
Peng Chen,Qibiao Wu,Jiao Feng,Lili Yan,Yitian Sun,Shuiping Liu,Yu Xiang,Mingming Zhang,Ting Pan,Xiaying Chen,Ting Duan,Lijuan Zhai,Bingtao Zhai,Wengang Wang,Ruonan Zhang,Ruonan Zhang,Bi Chen,Bi Chen,Xuemeng Han,Yicong Li,Liuxi Chen,Ying Liu,Xingxing Huang,Ting Jin,Wenzheng Zhang,Hong Luo,Xiaohui Chen,Yongqiang Li,Qiujie Li,Guohua Li,Qin Zhang,Lvjia Zhuo,Zuyi Yang,Huifen Tang,Tian Xie,Xiaoping Ouyang,Xinbing Sui,Xinbing Sui +37 more
TL;DR: The data suggest that the natural product erianin exerts its anticancer effects by inducing Ca 2+ /CaM-dependent ferroptosis and inhibiting cell migration, and erianIn will hopefully serve as a prospective compound for lung cancer treatment.
Journal ArticleDOI
Molecular targets of β-elemene, a herbal extract used in traditional Chinese medicine, and its potential role in cancer therapy: A review
Bingtao Zhai,Zhang Nana,Xuemeng Han,Qiujie Li,Mingming Zhang,Xiaying Chen,Guohua Li,Ruonan Zhang,Peng Chen,Wengang Wang,Li Chenxi,Yu Xiang,Shuiping Liu,Ting Duan,Lou Jianshu,Tian Xie,Xinbing Sui +16 more
TL;DR: The molecular mechanisms for the treatment effects on cancer of the herbal extract, β-elemene, which has been used for centuries in traditional Chinese medicine, are now being studied and identified.
Journal ArticleDOI
Baicalin induces ferroptosis in bladder cancer cells by downregulating FTH1
Na Kong,Na Kong,Xiaying Chen,Jiao Feng,Ting Duan,Shuiping Liu,Xueni Sun,Peng Chen,Ting Pan,Lili Yan,Ting Jin,Yu Xiang,Quan Gao,Chengyong Wen,Weirui Ma,Wencheng Liu,Mingming Zhang,Zuyi Yang,Wengang Wang,Ruonan Zhang,Bi Chen,Tian Xie,Xinbing Sui,Wei Tao +23 more
TL;DR: The data for the first time suggest that the natural product baicalin exerts its anticancer activity by inducing FTH1-dependent ferroptosis, which will hopefully provide a prospective compound for bladder cancer treatment.